Excited to share this work in which we show how infection, specifically UTI, can impact breast tissue through host-induced factors such as TIMP1, by this amazing team! Samantha Cyrill, PhD Mackenzie Callaway, PhD Deeptiman Chatterjee (He/Him) Michael Ciccone ⁦Camila dos Santos nature.com/articles/s4146…

Memory genes are enriched in CAR T cells that persist and control tumors in patients. But which transcription factors drive beneficial memory programs?

We answer this in our lab’s first paper in nature led by Alex Doan Kat Mueller, PhD Andy Chen. 1/

nature.com/articles/s4158…

Understanding precancers—early signs of cancer—
Out on Cancer Discovery for #AACR24 🇺🇸

involves analyzing genetic🧬 epigenetic, and environmental 🌳factors to prevent #cancer progression.

✅By integrating multi-omic data with patient metadata, we aim to develop effective interventions…

What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24 , out in Cancer Discovery today rb.gy/q484j9 Tweetorial👇

Interested in learning more about the many functions of Reactive Oxygen Species in cancer? Check out our recent review in Nature Cancer. Special thanks to Kat who in collaboration with Ahmed and Volkan Sayin Group put together this comprehensive review article nature.com/articles/s4301…

Best part of my job still...giving patients like Grady more hope. #HAI pump #ColorectalCancerAwarenessMonth Northwell Health Richard Barakat Matt Weiss youtu.be/VAC75f-hfGo?si…

TFW someone posts your first author manuscript and all you can think is what’s missing from this picture?

Happy to share our latest preprint in which we uncovered the potential of senolytic CAR T cells to promote tissue regeneration! Wonderful collaboration with Semir Beyaz AmorLab #Senescence #CART #Regeneration .
biorxiv.org/content/10.110…

Congrats, Alex Jaeger, well-deserved!

Proud of our surgical resident, Emma Gazzara, presenting our work on the role of Neutrophil Extracellular Traps as a immunotherapeutic target for colorectal liver Mets. Peter Westcott Mikala Egeblad Northwell Health Matt Weiss Gerardo Vitiello Danielle DePeralta Society of Surgical Oncology Jose M. Adrover

It was a great privilege to host the brilliant William L Hwang at our Defeating Cancer seminar series Cold Spring Harbor Laboratory! Thanks for an excellent seminar on innovative approaches to understanding tumor heterogeneity in #PDAC and compelling data on the active role of nerves in driving disease.

Congrats Xue-Yan He 何雪妍, Mikala Egeblad, et al., what an incredibly cool story, so great to see it out in its full glory Cancer Cell!

We've known how advanced cancer overrides our immune system. Now a new nature report on how early-stage, pre-cancerous cells can do that using an organoid colon cancer model
nature.com/articles/s4158…
Koch Institute at MIT Omer Yilmaz Judith Agudo

Best Bday gift ever! Happy bday to me!🤩 collaboration with gut stem cell super expert ⁦Omer Yilmaz⁩ to find how immunogenic Lgr5 cells can grow into tumors and evade immune surveillance. Team work makes the dream work (and the fun work!) nature.com/articles/s4158…

We are looking for a postdoctoral researcher 🧬🔬with a strong background in cancer biology and immunology for our lab at Cold Spring Harbor Laboratory! Please spread the word.
DM myself or Peter Westcott apply 👇👇👇👇
urldefense.com/v3/__https://w…$

Super cool!