🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Anti-CD20 monoclonal antibodies are therapeutic agents characterized by specific mechanisms of action & broad spectrum of clinical indications. Read this Editorial Commentary on advances, challenges, & future directions of anti-CD20. #OpenAccess link.springer.com/article/10.100…

The Professional Education Committee of the International Pediatric Nephrology Association (IPNA) was formed in 2019. Read this Editorial Commentary on IPNA webinars: an effective teaching platform advancing patient care in pediatric nephrology worldwide. link.springer.com/article/10.100…

AKI commonly occurs in critically ill children, but its impact on pediatric growth outcomes has been sparsely described. Read this Systematic Review /Meta-analysis comparing growth in children w/a history of AKI to those w/o AKI. #OpenAccess link.springer.com/article/10.100…

A 12-yr-old girl presented w/proteinuria & peripheral edema. Initial evaluation did not identify a clear underlying etiology. Read these Clinical Insights into idiopathic fibrillary glomerulonephritis in pediatric patients. link.springer.com/article/10.100…

AKI is highly prevalent among hospitalized children, but there is no treatment. Read this Original Article on pediatric AKI associated w/impairment in nicotinamide adenine dinucleotide (NAD+) metabolism. Amanda Clark, MD link.springer.com/article/10.100…

Uncontrolled diabetes mellitus (DM) accelerates atherosclerosis & vascular diseases. Read this Original Article on serum sclerostin as a marker of micro- & macrovascular complications among children & adolescents w/type 1 DM. #OpenAccess link.springer.com/article/10.100…

Glomerular diseases are a leading cause of CKD worldwide. Read this Review of monogenic podocytopathies & mechanisms by which single-gene defects lead to podocyte injury & glomerulosclerosis. Free access this month. bit.ly/4cUA5Us

UTI is a common bacterial infection in the pediatric population, & febrile urinary tract infection (fUTI) can lead to severe complications. Read this Original Article on the gut microbiome & metabolome in children w/a first fUTI. #OpenAccess link.springer.com/article/10.100…

AKI disproportionately impacts children in low- and middle-income countries, where up to 85% of AKI cases occur. Read this Review of global inequities in pediatric nephrology care & strategies to enhance diagnostics, treatment, & management of AKI & CKD. link.springer.com/article/10.100…

While critically ill children receiving continuous kidney replacement therapy (CKRT) are at increased risk of mortality, few studies have examined the predictors of mortality. Read this Original Article on CKRT outcomes & predictors of mortality. link.springer.com/article/10.100…

Nephropathic cystinosis is a lysosomal storage disease due to biallelic pathogenic variants in the CTNS gene encoding the cystine transport protein cystinosin. Read this Review of long-term outcomes in nephropathic cystinosis. Hayley Chang #OpenAccess link.springer.com/article/10.100…

Urinary biomarkers such as NGAL & renalase hold promise for assessing kidney health, yet their role in the pediatric neurogenic bladder remains unclear. Read this Original Article on their use in detecting kidney dysfunction. link.springer.com/article/10.100…

Virtually every protein in our bodies binds protons, resulting in a specific electrical charge. If the surrounding proton concentration changes, the charge of the protein can change. Read this Review of drug-induced acid–base disorders. link.springer.com/article/10.100…

Renal tubular dysgenesis (RTD) is a severe kidney disease w/poor development of proximal tubules & persistent fetal anuria leading to oligohydramnios. Read this Original Article on unsolved RTD w/low renin expression identified by whole genome sequencing. link.springer.com/article/10.100…

MYH9-related disease (MYH9-RD) is characterized by macrothrombocytopenia, hearing loss, & progressive kidney dysfunction. Read this Original Article on kidney pathological findings of MYH9-RD - a cross-sectional nationwide survey in Japan. link.springer.com/article/10.100…

Near-infrared spectroscopy (NIRS) is a relatively recent technology, first applied in clinical contexts in the early 1970s. Read this Educational Review of the use of NIRS to measure kidney oxygenation in the neonatal intensive care unit. link.springer.com/article/10.100…

Children w/CKD are at risk for deficiency or excess of magnesium & trace elements. Kidney function, dialysis, medication, & diet can affect their biochemical status. Read these Guidelines from the Pediatric Renal Nutrition Taskforce. #OpenAccess link.springer.com/article/10.100…

Ambulatory HT is associated w/elevated left ventricular mass index, cardiac dysfunction, & arterial stiffness in adolescents. Read this Original Article on ambulatory blood pressure variability in prediction of target organ injury - the SHIP AHOY study. link.springer.com/article/10.100…

Mineral bone disorder is a systemic disorder associated w/CKD. Read this Original Article on the impact of online hemodiafiltration - which combines hemodialysis & hemofiltration - on bone turnover in children w/CKD. #OpenAccess link.springer.com/article/10.100…

While hypertension (HT) in pediatric patients is often secondary (SH), recent trends show a rise in primary hypertension (PH). Read this Original Article on the etiology of HT & factors associated w/PH in a large European cohort of children. #OpenAccess link.springer.com/article/10.100…