Wow! So nice to see that the complex genetics of NK cell education revealed by Horowitz Lab @Icahn School of Medicine Mount Sinai has a role in AML and Immunotherapy. Makes perfect sense!

Thanks to Christina Tato Chan Zuckerburg biohub for very nice highlight of my 2013 CyTOF study with Parham Lab and Catherine Blish published Nature Rev Immunol. 1st report of human NK cells by CyTOF. nature.com/articles/s4157…

1/x. NK cell education is tightly linked to remodelling of the lysosomal compartment. Educated NK cells carry a greater cytotoxic payload in large dense-core secretory lysosomes (See T shirt). rdcu.be/bjoz0 @jodegoodridge Center for Infectious Medicine @UiO_LifeSci Nature Communications

**🚨 NEW PRE-PRINT🚨 ** So excited to share our work on KIR2DS4!!!! #NKcells #immunology #HLA

Our new review with Dr Emily Wroblewski is out now, studying Hominid species to understand 'the evolutionary dance between two cooperating systems of MHC class I and NK cell receptors' bit.ly/2Xg81Uw WUSTL Bioanthro

Review on how population genetics can greatly inform questions in human immunology Cell, see cell.com/cell/fulltext/…... and a great Cell's 2019 Special Issue: Unraveling the Human Genome! See cell.com/cell/issue?pii…

Super excited to see our paper finally out today pnas! A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson’s disease pnas.org/content/early/…

Our latest paper in collaboration with @PN0rmski and others out now, KIR and HLA class I diversity in Sub saharan African populations, 28 novel KIR alleles but surprisingly no new HLA alleles bit.ly/2OtRMiC

Our new perspective on the exciting research from Malcolm Sim and others, an encouraging step for identifying orphan KIR ligands and a role for NK cells in defense against bacterial infection.

Report from the Eleventh Killer Immunoglobulin-like Receptor (KIR) Workshop: novel insights on KIR polymorphism, ligand recognition, expression and f... - PubMed - NCBI Hoping to attend the next one in 2020, hosted by ⁦@PN0rmski⁩ ncbi.nlm.nih.gov/pubmed/3117763…

Altfeld and colleagues identify the NK cell receptor NKp44 as directly interacting with the class II HLA-DP in a partially peptide-dependent manner and with functional consequences for NK cell activity go.nature.com/2YzxEPD

Enhancing NK cell missing self responses with in vitro education by KIR3DL1. Our latest paper out now in LifeScienceAlliance life-science-alliance.org/content/2/6/e2…

Here’s our new paper — On genetic diversity in the human immune system — five years of research, led by postdoc Pippa Kennedy, and many collaborators. In Science Signaling stke.sciencemag.org/content/12/612…

Natural Killer cell research in Science Signaling ? Well isn’t that just a perfect Xmas present!

Our latest release from @DjaoudZ 'Dimorphism in the TCRγ-chain repertoire defines 2 types of human immunity to Epstein-Barr virus' bit.ly/2UDBcjH

Our latest release: HLAs, TCRs, and KIRs, a Triumvirate of Human Cell-Mediated Immunity. @DjaoudZ. annualreviews.org/doi/abs/10.114…

#JI_TopRead: From researchers Stanford Immunology Parham Lab @PN0rmski Prof Steven GE Marsh | Following Transplantation for Acute Myelogenous #Leukemia, Donor KIR Cen B02 Better Protects against Relapse than KIR Cen B01 #ReadTheJI ow.ly/R7pI50FqoGn

Very excited to say our paper exploring CD56neg NK cells has been published! Through a combination of meta-analysis, and both CyTOF and scRNAseq datasets, we investigate this unique population of NK cells linked to HIV-1 and other chronic virus infections frontiersin.org/articles/10.33…

Amazing paper by Dr Emily Wroblewski on Malaria-driven adaptation of MHC class I in wild bonobo populations - read it here! nature.com/articles/s4146…