Prof Param Mariappan 🇬🇧 🇲🇾 (@parammariappan) 's Twitter Profile
Prof Param Mariappan 🇬🇧 🇲🇾

@parammariappan

Husband, Dad | Urological Surgeon | Director Edinburgh Bladder Cancer Surgery @EdinSurg_BC | @Uroweb Bladder Cancer Guideline panels | Golfer. Views my own

ID: 1121858023591489536

calendar_today26-04-2019 19:26:10

2,2K Tweet

1,1K Followers

943 Following

Sabine D. Brookman-May (@brookmans76) 's Twitter Profile Photo

Would have loved to join this season Sarah P. Psutka MD MS Shilpa Gupta but not joining IBCG retreat this year 👉 still a way to go to develop the best endpoints in IR #NMIBC that make clinical and regulatory sense and for from a #patient perspective Ashish M. Kamat, MD, MBBS Roger Li

Joan Palou Redorta (@joanfundi) 's Twitter Profile Photo

When friendship facilitates working together and improve patient care with #bladdercancer. #IBCG as a pushing and opening minds in order to progress in the diagnosis management!

Prof Param Mariappan 🇬🇧 🇲🇾 (@parammariappan) 's Twitter Profile Photo

Thank You for the inspiring and inclusive leadership, Ashish M. Kamat, MD, MBBS. Roger Li IBCG Bladder-sparing Therapy for Bacillus Calmette-Guérin–unresponsive Non–... sciencedirect.com/science/articl…

Thank You for the inspiring and inclusive leadership, <a href="/UroDocAsh/">Ashish M. Kamat, MD, MBBS</a>.

<a href="/UrogerliMD/">Roger Li</a>      <a href="/IBCG_BladderCA/">IBCG</a> 

Bladder-sparing Therapy for Bacillus Calmette-Guérin–unresponsive Non–... sciencedirect.com/science/articl…
Ashish M. Kamat, MD, MBBS (@urodocash) 's Twitter Profile Photo

Timely! Just out from #IBCG23 as we wrap up #IBCG24: Bladder-sparing Therapy for BCG–unresponsive NMIBC: International Bladder Cancer Group Recommendations for Optimal Sequencing and Patient Selection authors.elsevier.com/a/1jfA914kplyy… IBCG World Bladder Cancer Patient Coalition Bladder Cancer Advocacy Network

Timely! Just out from #IBCG23 as we wrap up #IBCG24: 
Bladder-sparing Therapy for BCG–unresponsive NMIBC: International Bladder Cancer Group Recommendations for Optimal Sequencing and Patient Selection 
authors.elsevier.com/a/1jfA914kplyy…

<a href="/IBCG_BladderCA/">IBCG</a> <a href="/WorldBladderCan/">World Bladder Cancer Patient Coalition</a> <a href="/BladderCancerUS/">Bladder Cancer Advocacy Network</a>
World Bladder Cancer Patient Coalition (@worldbladdercan) 's Twitter Profile Photo

#IBCG24 Retreat, the IBCG continues to lead the way in addressing global educational needs and learning gaps in order to improve care for people affected by #bladdercancer around the 🌎 All through proactive and dedicated global collaboration. A big thank you to

#IBCG24 Retreat, the <a href="/IBCG_BladderCA/">IBCG</a> 
continues to lead the way in addressing global educational needs and learning gaps in order to improve care for people affected by #bladdercancer around the 🌎 All through proactive and dedicated global collaboration. 

A big thank you to
World Bladder Cancer Patient Coalition (@worldbladdercan) 's Twitter Profile Photo

🌟 Flashback to #BladderCancerForum23! 🗣️ Watch Petros Grivas share invaluable insights from last year’s event. Ready for more? Don’t miss out on the 2024 Forum - secure your spot today! 👉ow.ly/joRp50T82C0

Tom Powles (@tompowles1) 's Twitter Profile Photo

The EMA has approved Enfortumab Vedotin and pembrolizumab for 1st line urothelial cancer. It supersedes 1st platinum based therapy as the new standard of care in Europe. astellas.com/en/news/29371?…

Prof Param Mariappan 🇬🇧 🇲🇾 (@parammariappan) 's Twitter Profile Photo

Pleased to share the collaborative work between Sweden, Scotland and European Association of Urology (EAU) #NMIBC guidelines panel - a dataset of 9710 primary #NMIBC patients. This analysis describes the value in stratifying HG to HG/G2 and HG/G3. authors.elsevier.com/sd/article/S03…

Pleased to share the collaborative work between Sweden, Scotland and <a href="/Uroweb/">European Association of Urology (EAU)</a> #NMIBC guidelines panel - a dataset of 9710 primary #NMIBC patients. 

This analysis describes the value in stratifying HG to HG/G2 and HG/G3. 

authors.elsevier.com/sd/article/S03…
Ashish M. Kamat, MD, MBBS (@urodocash) 's Twitter Profile Photo

Bowling for Bladder Cancer 🇺🇸 🇨🇦 🇬🇧 🇮🇹 🇳🇱 🇩🇪 🇦🇺 🇮🇳 🇲🇦 🇬🇷 🇨🇱 #IBCG24 IBCG #BladderCancer

Bowling for Bladder Cancer

🇺🇸 🇨🇦 🇬🇧 🇮🇹 🇳🇱 🇩🇪 🇦🇺 🇮🇳 🇲🇦 🇬🇷 🇨🇱

#IBCG24 <a href="/IBCG_BladderCA/">IBCG</a> #BladderCancer
UroToday.com (@urotoday) 's Twitter Profile Photo

Guidelines aim to harmonize and optimize urothelial carcinoma clinical trials. Ashish M. Kamat, MD, MBBS and Matt Galsky join Sam S. Chang MD, MBA to discuss new trial parameters and the urgent need for detailed guidelines due to the dynamic landscape of treatment > bit.ly/4bcYVxh

Guidelines aim to harmonize and optimize urothelial carcinoma clinical trials. <a href="/UroDocAsh/">Ashish M. Kamat, MD, MBBS</a> and <a href="/MattGalsky/">Matt Galsky</a> join <a href="/UroCancerMD/">Sam S. Chang MD, MBA</a> to discuss new trial parameters and the urgent need for detailed guidelines due to the dynamic landscape of treatment &gt; bit.ly/4bcYVxh
Tom Powles (@tompowles1) 's Twitter Profile Photo

Perioperative durvalumab + neoadjuvant chemo & cystectomy in operable bladder cancer significantly delays (HR 0.68) event free survival and a 25% reduction in the risk of death. 10% ⬆️ pCR. It’s the 1st time immune therapy has an OS benefit in muscle invasive UC #ESM024 NEJM

Perioperative durvalumab + neoadjuvant chemo &amp; cystectomy in operable bladder cancer significantly delays (HR 0.68) event free survival and a 25% reduction in the risk of death. 10% ⬆️ pCR. It’s the 1st time immune therapy has an OS benefit in muscle invasive UC #ESM024  <a href="/NEJM/">NEJM</a>
Sabine D. Brookman-May (@brookmans76) 's Twitter Profile Photo

Updated #SunRISe1 study results of 3 cohorts in BCG-unresp HR #NMIBC #ESMO24 C1: #TAR200🥨 + CET (n=53) C2: TAR-200 alone (n=85) C3: CET alone (n=28) ✅ CR at any time: C1 - 68%; C2 - 84%; C3 - 46% ✅ Estimated 12 months DOR rate in pts with TAR-200 monotherapy 65.7%

Updated #SunRISe1 study results of 3 cohorts in BCG-unresp HR #NMIBC #ESMO24 
C1: #TAR200🥨 + CET (n=53)
C2: TAR-200 alone (n=85)
C3: CET alone (n=28)
✅ CR at any time: C1 - 68%; C2 - 84%; C3 - 46%
✅ Estimated 12 months DOR rate in pts with TAR-200 monotherapy 65.7%
Lars Dyrskjøt (@ldyrskjot) 's Twitter Profile Photo

Exited to share the first results from the TOMBOLA trial presented at #ESMO24 by Jørgen Bjerggaard. We used tumor informed (WES; ddPCR) ctDNA analysis to guide Atezolizumab treatment after cystectomy using longitudinally collected blood samples. Key findings: •CtDNA-negative

Exited to share the first results from the TOMBOLA trial presented at #ESMO24 by <a href="/JBjerggaard/">Jørgen Bjerggaard</a>. We used tumor informed (WES; ddPCR) ctDNA analysis to guide Atezolizumab treatment after cystectomy using longitudinally collected blood samples.  

Key findings:

•CtDNA-negative
Tom Powles (@tompowles1) 's Twitter Profile Photo

Perioperative Durvalumab with Neoadjuvant Chemotherapy in Operable Bladder Cancer is the 1st perioperative immune therapy study to show an OS in bladder cancer. Published in @nejm gbr01.safelinks.protection.outlook.com/?url=https%3A%…