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🚨Our📜officially out in June issue of Cancer Discovery Cancer Discovery AACR! Thank you #DattaLab members esp Anna Bianchi, PhD, mentor Nipun Merchant, collaborators Ben Stanger Eneda Toska Lab Gabrilovich Lab, sponsor Stephen D. Nimer, MD & funders PanCAN #PardeeFdn Assoc4AcademicSurgery American College of Surgeons

📢📢Spreading the word!!! Our Center, Henry Ford Pancreatic Cancer Center, is hiring a Grants manager!! If you are or know of someone who might be interested, please reach out!!! henryford.referrals.selectminds.com/jobs/research-…

Submit an abstract by July 13 for the AACR Special Conference on Pancreatic Cancer (Sept 27-30, Boston), chaired by Christine A. Iacobuzio-Donahue, Anirban Maitra, Rosalie C. Sears, and Jen Jen Yeh. bit.ly/3WReKmK #AACRpan23 Chris Iacobuzio Anirban Maitra Rosie Sears Yeh Lab

Teaser #PREOPANC2 design & accrual: Total #Neoadjuvant #FOLFIRINOX in resectable + borderline resect #PancreaticCancer vs “winning arm” #PREOPANC trial #EAHPBA2023: accrual faster than planned ✅, final survival outcome expected in Sept 2023 ✅ @EmmelieDekker Bas Groot Koerkamp

Excited to present our #PancreaticCancer stromal subtyping work at the PDAC Stromal Reprogramming Consortium meeting today in Ann Arbor Michigan with Yeh Lab Xianlu Laura Peng Susan Tsai, MD, MHS! Had a lovely dinner last night with other U01 sites at Zingerman's roadhouse. Big thanks to the organizers

Fantastic keynote by Shah Lab at PDAC Stromal Reprogramming Consortium consortium meeting on hypoxia, lipids and gases in cancer. Thank you PascaLab Lyssiotis Lab timofran for inviting Dr. Shah for this meeting.

Now online in Cancer Discovery: #SpatialTranscriptomics of Intraductal Papillary Mucinous Neoplasms (#IPMN) of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential Marta Sans Escofet Anirban Maitra MD Anderson Cancer Center doi.org/10.1158/2159-8…

New one in Cancer Discovery from the Anirban Maitra Lab! Check it out!! aacrjournals.org/cancerdiscover…

So happy to have our study now out in Cancer Discovery!! We used #SpatialTranscriptomics and COMET imaging to spatially profile IPMN lesions of the #pancreas and identified NKX6-2 as a previously unknown transcription factor driving indolent gastric differentiation.

The Visium spatial transcriptomics data of human and murine IPMN samples from our Cancer Discovery paper is available at GEO for download at: ncbi.nlm.nih.gov/geo/query/acc.… Hopefully will be useful to the #PancreaticCancer research community. aacrjournals.org/cancerdiscover…

From the June issue— Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Pre-Neoplastic #Pancreatic Lesions, by PascaLab, timofran et al. bit.ly/3P3wXf8 •UMPCR• U-M Rogel Cancer Center Michigan Surgery #PanIN #PancreaticCancer

Featuring the opus that was @_sunnydae9's wide-ranging and outstanding dissertation work in #cancercachexia and #PancreaticCancer. Want to drive this project now? We are hiring! OHSU Knight Cancer Institute 🌉🛶🚠🚵‍♂️🗻🌊🧪🫂

Submit an abstract by July 13 for the AACR Special Conference on Pancreatic Cancer (Sept 27-30, Boston), chaired by Christine A. Iacobuzio-Donahue, Anirban Maitra, Rosalie C. Sears, and Jen Jen Yeh. bit.ly/3qDYFos #AACRpan23 Chris Iacobuzio Anirban Maitra Rosie Sears Yeh Lab

Hey Mom, I'm on the radio! This was a fun experience. Thanks to Kelly Cutrara the opportunity to raise awareness for #PancreaticCancer and discuss our new study! cc: U-M Rogel Cancer Center, •UMPCR•, UMPhysiology, PanCAN pdst.fm/e/chtbl.com/tr…

Letters of Intent for CDMRP #PancreaticCancer Research Program are due in one month. PanCAN Allison Rosenzweig cdmrp.health.mil/funding/pcarp

From Inserm Rémy Nicolle et al in Nature Communications Pacpaint: a histology-based deep learning model uncovers the extensive intratumor molecular heterogeneity of #PancreaticCancer nature.com/articles/s4146… ~40% of RNA defined “classical” cases harbor “basal-like” component on #AI

Out in Nature Communications from the Johns Hopkins Kimmel Cancer Center team: A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable #PancreaticCancer Dr. Elizabeth Jaffee nature.com/articles/s4146…

The pancreatic microenvironment may contribute to cancer onset and spread, according to research published in Cancer Discovery and presented at #AACRras23. Learn more on the #AACRBlog: bit.ly/3JnsvEp Michigan Medicine

#ICYMI from the June issue— In the Spotlight: #Pancreatic neoplasms are frighteningly common: A role for immune surveillance? By Megan T. Hoffman and Stephanie K. Dougan. bit.ly/4410ScI Dana-Farber Dana-Farber News Harvard Medical School

Spatial determination and prognostic impact of the fibroblast transcriptome in #PancreaticCancer elifesciences.org/articles/86125 Tumor proximity determines state: “Tumor proximal” - enriched in myCAFs, wnt ligands “Tumor distant” - enriched in iCAFs, complement, wnt inhibitory signals