Our paper on meiotic telomere tethering to the nuclear membrane by MAJIN-TERB2-TERB1 has now been published in Nature Communications doi.org/10.1038/s41467…

We have a PhD position available to study the structure of the synaptonemal complex through cryo-EM, X-ray crystallography and biophysics. Application deadline 11th January. findaphd.com/phds/project/t…

It doesn’t always require a crystal to solve the structure of a coiled-coil protein! Our paper on the structure of synaptonemal complex protein SYCE1, determined by solution small-angle X-ray scattering, is now available on-line. rdcu.be/bfGC2

And last up for today Owen Davies' talk: CCP4 SW2019 - Solving coiled coil structures through unconventional MR m... youtu.be/CkpQxnH-C3I via YouTube

Lonely Cyclin B1 molecules are readily exterminated in oocytes. Work from Suzanne Madgwick's lab on Cyclin degradation in meiosis has just been published in Developmental Cell. cell.com/developmental-…

Mechanism of SYCE3 self-assembly within the synaptonemal complex revealed through SAXS analysis coupled with molecular modelling, now available in Biorxiv: A molecular model for self-assembly of synaptonemal complex protein SYCE3 biorxiv.org/content/10.110…

Our paper on the mechanism of SYCE3 self-assembly has now been published in JBC: jbc.org/cgi/content/lo…

Here's an exciting, multi-disciplinary BBSRC PhD opportunity with Owen Davies Lab (mainly; xtal, cryoEM) and me (bioinformatics) on the structural biology of meiotic recombination. Cancer drug targets too. @LivUniLifeSci @livuniIIB LivUniHLSPGR findaphd.com/phds/project/t…

Our collaborative work with Alberto Pendas on the synaptonemal complex SYCE1-SIX6OS1 interaction and its role in infertility has just been published in Science Advances: advances.sciencemag.org/content/6/36/e…

Our structural studies reveal that SUN-KASH complexes are head-to-head 6:6 assemblies, leading to a new model for LINC complex architecture. Now published in eLife: doi.org/10.7554/eLife.…

Our work on how synaptonemal complex component SYCE2-TEX12 mediates meiotic chromosome synaptic elongation by assembling into 'intermediate filament'-like fibres has just been published in NSMB NatureStructMolBiol: nature.com/articles/s4159…

We have postdoc positions available in structural and cellular biology, studying supramolecular assembly of the synaptonemal complex in meiosis. Contact me directly for information. For details and to apply (deadline 20th January): tinyurl.com/3xbdeu62 tinyurl.com/ycktp2k9

Save the date! The 2023 British Meiosis Meeting #BMM2023 will be held in Edinburgh on 19-20th April. We have many opportunities for post-docs and students to present - and two amazing colleagues Borde Lab @weir_science as guest speakers. Ian R Adams Owen Davies Lab

Our work on the structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3 has now been published in NatureStructMolBiol. This biochemical and mouse genetics paper resulted from an excellent collaboration with Ian R Adams. nature.com/articles/s4159… rdcu.be/c3i5E