Oren Friedman
@orenfriedman
Resuscitationist. Pulm-crit doc that's into Echo, PE, cardiac arrest, and ECMO. I love teaching critical care and forever learning critical care
ID: 2607247127
13-06-2014 21:45:10
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Guidelines recommend use of alternatives to UFH in acute PE due to the unpredictable pharmacokinetics of UFH (the rollercoaster) & resource intensity. we looked at nearly 300,000 patients hospitalized w/acute PE to see if we're doing that AnnalsofEM authors.elsevier.com/a/1jHL3ib7EM8JM (1/)
๐ฉธRecent systemic thrombolysis per sรจ should NOT be considered contraindication for initiating #ECLS in high-risk PE. Study including pts undergoing/not to pre #ECMO cannulation thrombolysis: no difference in survival/bleeding risk #FOAMcc Intensive Care Medicine ๐ rdcu.be/dLOBk
How would you handle this one PERT colleagues ? John Moriarty James Horowitz myda Parth Rali F Mae West, MD MS
STRIKE-PE trial data drop: Impressive improvements in QOL post PE-intervention. Thx patients and investigators on 3 continents, more to come soon! sciencedirect.com/science/articlโฆ. JVIR Society of Interventional Radiology PERT Consortium UCLA IR UCLA Pulmonary Vascular Disease Program UCLA Health
Landmark PERSEVERE trial announced European Society of Cardiology 2024 RCT for high risk massive PE: large bore thrombectomy vs standard of care. Mortality 20-30% with standard of care 1 past RCT in this group with only 8 patients. The โGolden Era of PE RCTโ continues! sciencedirect.com/science/articlโฆ
Asher Mendelson, MD PhD Oren Friedman European Society of Cardiology protocol-specified absolute CI are trial exclusions. These include intracranial malignancy, active bleeding, stroke within 14 days, and spine/brain surgery within 14 days. Goal is for pragmatic, strategy trial so other high risk features for bleeding will ideally be randomized