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#BigData in #MS - a great overview of the incorporation of all the -omics (genomic, metabolomics, proteomics, etc) towards novel understanding and treatments for #PMS #ProgressiveMS

#BrainAtrophy and #CognitiveImpairment in #MS - Closely interlinked, and of great importance to PWMS. Cognitive impairment being associated with more care needs and worse quality of life - focus on slowing/stopping this is essential!

An excellent overview of #SMOULDERINGMS - how we see progression independent of relapses #PIRA, what processes are involved and what #biomarkers will let us ultimately lead to individualized treatment!

What is MS progression? Our understanding of progress independent of disease activity (PIRA) has grown over the last 20 years, with clinical and real world studies confirming that once relapses are controlled with DMTs progression can still happen!

Excellent European Academy of Neurology #EAN2023 update on our expanded knowledge of #MS CNS compartmentalised inflammation and the exciting near future of BTK Inhibitors by Wallace Brownlee, Veronica Popescu and Martin König Wallace Brownlee Veronica Popescu

Thank you Stuart Nixon MBE+Marie for inspiring work MS Society UK MS Society Cymru Ambassadors for people with #MS #AdvancedMS Check out chariotms.com #ChariotMS QueenSquareMSCentre MS-STAT2 OctopusTrial AttackMS the_MSBlog #MS Rachel Horne theMSguide.com 🧠 Patrick B, I walk very slowly #NHS75 #GIG75

Great read about the first patient on the Welsh arm of the OCTOPUS trial! bbc.co.uk/news/uk-wales-…

Great feature by ITV News on the Octopus trial - helping to raise awareness of both progressive MS and the study. itv.com/news/wales/202…

Designing a MAMS trial with binary outcome? Want to optimise it? Need accurate trial timelines, based on realistic assumptions? Then read our article & use latest additions to the nstage software: journals.sagepub.com/doi/epub/10.11… Max Parmar MRC Clinical Trials Unit at UCL UKCRC CTU Network SCTorg ICTM at UCL

Long-term treatment with anti-CD20 mAbs - is it feasible? What are the risks? From Emma Tallantyre, MD, PhD, Cardiff University, Cardiff, UK. youtu.be/pZRFNVEt3oA?si…

🚨Exciting news! Our latest podcast mini-series is here and it's all about OctopusTrial🐙 Octopus is funded by MS Society UK to test new treatments for progressive #MultipleSclerosis. Episode 1 covers the current #MS research landscape. Listen now🎧👉bit.ly/3S6FKP4

Part 1/4: Professor Chataway speaks with the Trails Talk team about MS, why we need MAMS trials for PMS, and how the OCTOPUS trial was designed open.spotify.com/episode/5WPqrg…

Very proud to share our results regarding the use of #MTR in evaluating the pathological mechanism of the #opticneuritis QueenSquareMSCentre #SIN2023 #SigN

We're very excited to share the final part of our Octopus podcast mini-series!🎙️ This episode is all about #PatientPublicInvolvement #PPI and how people affected by #MultipleSclerosis shaped the OctopusTrial MS Society UK. Listen to the final episode👉bit.ly/49vmtwY

Great Investigator Meeting with our fantastic colleagues across the UK! Talks all about the outstanding work that's gone into setting up and starting the OCTOPUS trial, and the exciting plans moving forwards! MS Society UK MRC Clinical Trials Unit at UCL

It's gone GLOBAL! mssociety.org.uk/research/lates… Platypus is the Australian extension of OCTOPUS, anyone with Progressive MS can sign up via the same registration of interest portal to take part: ukmsregister.org/octopus

Fantastic workshop MRC Clinical Trials Unit at UCL this week sharing and learning from the experiences of other #MAMS #trials including EJS ACT-PD OctopusTrial MND-SMART followed by another inspiring session led by our brilliant rising stars of the #acord fellows academy 👏🏾

Registration and abstract submission are open for MS Frontiers conference! This year the MS Society are hosting their MS research conference at the University of Liverpool. Find out all about it and how to register via their website: mssociety.org.uk/research/for-r…

Registration and abstract submission are open for MS Frontiers conference! This year the MS Society are hosting their MS research conference at the University of Liverpool. Find out all about it and how to register via their website: mssociety.org.uk/research/for-r…

Comorbidity in the multiple sclerosis clinic: doi.org/10.47795/QORZ6…