🧵 New Special Communication examines drawing causal inferences about the effects of interventions from observational studies in medical journals and suggests a framework that might be used.

ja.ma/3UxeAjL

Privileged to think & write w/ James Januzzi Jr MD

We discuss:
1. Startling amount of silent heart disease in ex-football players ( #HuddleStudy )
2. Critical need for post-career primary care
3. Importance for all players, especially those from Black communities

bit.ly/3UR1Zt6

La supervivencia de las personas que inician diálisis por lesión renal aguda y cirrosis es de solo 20% a 6 meses, por ello desarrollaron el modelo multidisciplinar SILK, para ayudar en la toma de decisiones y plantear objetivos

Kidney360
10.34067/KID.0000000000000382

In lockstep with the ASCO Presidential Theme ASCOPres - Palliative Care is on the stage as a PLENARY at this year's Annual Meeting

This kind of research matters - has reach, clinical practice, and policy implications

meetings.asco.org/abstracts-pres…

📣 Together with hutlab Lisa Strate and led by Wenjie Ma, we report unique inflammation-related microbial and metabolic signatures in diverticulitis Yiqing Wang long nguyen Raaj Mehta, MD, MPH Mingyang Song Clinical & Translational Epidemiology Unit - MGH MGH Division of Gastroenterology Mass General Research Institute

🔗nature.com/articles/s4146…

Important trial alert

Nina Kimer with ANOTHER huge trial in #cirrhosis care

Post-discharge intervention (home visits, phone calls, education) did not improve readmissions, survival, or quality of life - but some bright spots in secondary outcomes

journals.lww.com/hepcomm/fullte…

The evidence speaks for itself…. Minimum Alcohol Pricing reduces alcohol-related deaths and alcohol-related liver disease. It’s time for action British Liver Trust Victoria Atkins Alcohol Health Alliance UK BSG Dr Rachel Clarke BASL Shaun Lintern Ross Lydall The BMJ The Lancet Gastroenterology & Hepatology

A key teaching point I have held onto from HMS Palliative Care #PCEP course is the importance of improving symptom burden prior to serious illness discussions to allow patients to have the physical/mental space to think more clearly about their priorities Vicki Jackson Shunichi Nakagawa

Our new Nature Medicine paper describes the results of our search for proteins secreted by the placenta that modulate insulin resistance in pregnancy! nature.com/articles/s4159…

Also loved spending QT with MGH Division of Gastroenterology rockstar 3rd yr fellows (I kinda look like a fellow in these too 😂).

The future is bright!🌟🌟💥💥 #ScrubsNHeels24

SO honored to have J. Sawalla Guseh, M.D., 🏊‍♀️ 🚵‍♀️🏃‍♂️sport cardiologist 🫀 expert & 🐍 wrangler extraordinaire, visit as our annual Fellow’s Visiting Professor Grand Rounds invited speaker! He’s invited to be on our team any day! #honorarywolverine 〽️🐺💙
Mass General Heart U-M Health Frankel CVC

Acute-on-chronic liver failure (ACLF) is a morbid diagnosis that carries high risk of short-term mortality. This Perspective describes a framework to guide the difficult conversations regarding initiating RRT to ease distress for all parties involved bit.ly/KID0382

just heard amazing data about the alive service at MGH Division of Gastroenterology . Encourages aud therapy and prevents liver events in patients with alcohol use. Great presentation! Please consider inviting Jay Luther Jay Luther to present. #livertwitter AASLD American Gastroenterological Association (AGA)

Guidelines are unanimous;

For look risk procedures like paracentesis we need not check INR and should not give FFP

Liver, gastroenterology, hematology, and interventional radiology societies agree

So why the variation in managing “the cirrhotic coagulopathy”?

🧵

#MonganScienceMinute featuring Nneka N. Ufere, MD MSCE Areej El-Jawahri Mass General Cancer Center pubmed.ncbi.nlm.nih.gov/38497942/

HCV treatment via telemedicine integrated with addiction care.

92% DAA initiation.

ITT cure rate of 90% with telemed vs 39% usual care. Population - people with opioid use disorder. Trial was pragmatic.

Programs like these should be implemented WIDELY
bit.ly/3TCfxHa

Out now 💥 pragmatic RCT which found higher HCV cure rates with facilitated telemedicine integrated into opioid treatment programs led by Dr. Andrew Talal at UBuffalo. Proud to be part of this study. Michigan Hepatology MountSinaiLiver #livertwitter

With tremendous joy, I share that our patient who received a gene-edited pig kidney transplant was discharged home today after removal of his dialysis access. We hope that this is a first step that will bring hope to many patients waiting for a kidney transplant #xenotransplant

We are happy to share that today, Rick Slayman, our first patient to ever receive a genetically edited pig kidney transplant, has been discharged from the hospital. He is recovering well and will continue to recuperate at home with his family.

Had our first LiverPal semi-annual retreat yesterday. Beautiful opportunity for reflection on the journey thus far. Forever thankful and grateful to work with this team. 6 months down, 40 patients randomized! #palliativehepatology