Did you know? Zebrafish are more closely related to fish than to zebras. #ZebrafishFunFacts

Delighted to share our latest work published in Nature Communications! We show that non-coding enhancer transcription can flexibly modulate the efficiency of burst induction from linked gene either negatively or positively by changing the size of transcription hub. nature.com/articles/s4146…

Happy to announce publicly that I was awarded a K99/R00 from NCI! Big thanks to Proud Cliff Brangwynne brangwynnelab and my co-mentor on this project Cigall Kadoch Cigall Kadoch Looking forward to big discoveries!

In this study, Nicholas Treen et al. describe a temporal transcriptional switch in the chordate embryo, regulated by FGF signaling. Read more about it here: ➡️genesdev.cshlp.org/content/early/…

My image was featured on the cover of the latest issue of Genes & Development! You can read the paper here: genesdev.cshlp.org/content/37/3-4…

Levine lab reunion! It was great to see my former colleagues in Princeton, Nick Nicholas Treen João João Raimundo Laurence and Bomyi!!

How do distal enhancers control transcription dynamics in living cells? Check out our latest work published in Molecular Cell!! We show that the dynamic assembly and disassembly of TF clusters at enhancers are a major source of transcriptional bursting. cell.com/molecular-cell…

no it’s the misogyny

Delighted to share a short review article published in Science Advances!! Enhancer dynamics: Unraveling the mechanism of transcriptional bursting. science.org/doi/10.1126/sc…

So excited to join the Dept of Biochemistry & Molecular Biophysics Biochemistry & Molecular Biophysics and the Program for Mathematical Genomics!!! I am extremely grateful to Stavros and many others for the warm welcome, and greatly looking forward to learning, discussing & collaborating together.

Delighted to share our new pre-print and introduce the mTurq2-Col4a1 mouse model in which collagen IV is endogenously tagged - thanks to all authors! A Window into Mammalian Basement Membrane Development: Insights from the mTurq2-Col4a1 Mouse Model biorxiv.org/content/10.110…

Very happy to have this research project from my postdoc with @EKfarley out in Dev Cell! We wondered if single-nucleotide variants within heart enhancers can affect enhancer activity and phenotype.

New paper alert! Working with @CALM_STP The Francis Crick Institute Princeton University we have developed a method to stage zebrafish embryos using deep learning 💻📷 Many thanks to my co-authors David Barry and Matt Renshaw, as well as Triveni Menon,Dr. Rebecca Burdine - (Black lives matter!) Gary Laevsky @glaevsky.bsky.social and Danelle Devenport 💙

The fruit fly Drosophila melanogaster- expertly illustrated by Mike Levine

A clever strategy for multiplexed immunolabeling out today from Peng Yin's lab. "Thermal-plex" uses DNA probes that fluoresce sequentially when, and only when, activated with transient exposure to heating spikes at designated temperatures. nature.com/articles/s4159…

Kudos!👏 to Harsha Sen, 3rd-year grad student in @R_Mallarino lab, awarded Best Student Talk in Division of EvoDevo Bio at 2024 meeting of Society for Integrative and Comparative Biology #SICB2024. The talk: "Molecular evolution and development of the mammalian gliding membrane."

Chromatin scientists, want to reorganize genomic loci as you wish? Out today in Cell--We made a tool that uses surface tension of engineered condensates to reposition DNA loci across microns of space in living cells in just a few minutes: VECTOR cell.com/cell/abstract/…

What if you could deliver molecular tools directly into oocytes without microinjection? In our new paper, online today Development (doi.org/10.1242/dev.20…), we introduce VitelloTag, a new cargo delivery tool to enable injection-free genome editing. 👇Read on for a short 🧵