How can we measure acetylcholine levels in vivo? Discussion of old and new approaches. Marina Picciotto doi.org/10.1111/jnc.15…

Dopaminergic D2 receptor modulation of striatal cholinergic interneurons governs sequence learning biorxiv.org/cgi/content/sh… #biorxiv_neursci

A little late to the NOA sharing, but the lab recently got its first NIH grant - a R03 from NIAAA News! Many thanks to colleagues and collaborators for discussion and edits. Now back to the R01 apps 😬

Excited that the first pre-print from the lab is up on BioRxiv! Dr. Chen, a post-doc in the lab did a really nice direct comparison of two types of neurons known to degenerate in Parkinson's Disease.

Bed Nucleus of the Stria Terminalis (BNST) neurons containing the serotonin 5HT2c receptor modulate operant alcohol ... biorxiv.org/cgi/content/sh… #biorxiv_neursci

I’m so excited to share that my paper is now online at Cell Reports! We use optical imaging to examine the spatial organization of presynaptic calcium signals. More details below 🧵👇 cell.com/cell-reports/f…

A dual-pathway architecture enables chronic stress to promote habit formation biorxiv.org/cgi/content/sh… #biorxiv_neursci

Congrats all! This paper is definitely on the list for lab journal club next semester.

Striatal neurons are recruited dynamically into collective representations of self-initiated and learned actions in freely-moving mice eneuro.org/content/early/…

Alpha-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinsons disease biorxiv.org/cgi/content/sh… #biorxiv_neursci

Transcriptional correlates of cocaine-associated learning in striatal ARC ensembles. biorxiv.org/cgi/content/sh… #biorxiv_neursci

My final postdoc paper is 'finally' out and published in NatNeu. I consider this the best work I have been involved in. Here, we present evidence of a systematic change in how the striatal dopamine signal integrates reward time horizons. nature.com/articles/s4159…

‘Seek Funding’ Step Added To Scientific Method bit.ly/4b3yWrG

Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum biorxiv.org/cgi/content/sh… #biorxiv_neursci

An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes

Proof

Do you know how to recognize signs of Parkinson's disease in yourself or a loved one? Visit Parkinson.org/EarlySigns to familiarize yourself with 10 early signs of PD. 🧠

First alcohol lab paper out today! Neurotoxic effects of chronic ethanol on cholinergic interneurons in the dorsomedial striatum. doi.org/10.1016/j.neur… Many thanks to all contributors!