A true collaboration. Congrats to #UWMadisonChem Lingjun Li's contribution to "Diazobutanone-assisted isobaric labelling of phospholipids and sulfated glycolipids enables multiplexed quantitative lipidomics using tandem mass spectrometry" loom.ly/8XJq6Us

Today we report in Nature Communications the development of laboratory-evolved CBE6 cytosine base editors that offer high on-target C•G-to-T•A editing, virtually no A•T-to-G•C editing, low off-target editing, broad sequence context compatibility, and compatibility with multiple Cas

I’m thrilled to share the results from the first project of my PhD! Huge thanks to my co-authors Monica Elena Neugebauer and Nicholas Krasnow for their contributions and support throughout the project. Very excited to see how the community will use these next-generation base editors!

Meet Prof. Phillip Milner Milner Group at Cornell University @cornell, a 2023 ACS Materials Au Rising Star. Check out Phillip's work here 🔓 👉 go.acs.org/8fM

Interested in graduate education in the biomedical sciences? Please consider applying!

Today in @Science_Magazine we report the laboratory evolution of compact degrons that enable targeted protein degradation triggered by an otherwise-inert small molecule, a multidisciplinary study that integrates organic chemistry, molecular glues, protein evolution, genome

Congratulations to Judith Simcox PhD on winning the Shaw Award! Join us in 214A now for her talk! #MassSpec #Lipids #DiscoverBMB asbmb.org/asbmb-today/pe…

We are recruiting a PhD-level project scientist for our rapid antibody evolution projects and to coordinate the growth of our efforts in this area. Please apply here: recruit.ap.uci.edu/JPF08912

Please RT: The Walter lab at Harvard seeks computational biologists to extend our work using AlphaFold to find new protein-protein interactions. Contact [email protected] biorxiv.org/content/10.110… predictomes.org

Some say hybrid comp/expt labs, where dry lab meets wet lab, are "at the beach". Hbt "the shore of Lake Mendota" ? I'm thrilled to join Biochemistry at UW-Madison! Starting 2025, the Wayment-Steele lab will unite AI & experiment to transform how we study biomolecular dynamics.

.UW-Madison Chemistry scientists have developed the most sensitive method yet for detecting and profiling a single molecule — unlocking a new tool that holds potential for better understanding how the building blocks of matter interact with each other. news.wisc.edu/uw-madison-sci…

Today we report in Nature Biomedical Engineering the eePASSIGE system, which uses evolved and engineered recombinases and prime editing to integrate large gene-sized DNA cargoes into the mammalian genome in an efficient, precise, and targeted manner. (1/13) drive.google.com/file/d/1WDMVqL…

A new version of prime editing makes gene-sized edits in human cells at therapeutic levels — and could pave the way to one-size-fits-all gene therapies for diseases such as cystic fibrosis. broad.io/eePASSIGE-news

We're hiring! The Procurement Specialist will support the department's researchers and state-of-the-art facilities by researching, creating, and soliciting bids and proposals from third party suppliers. Apply by July 8: jobs.wisc.edu/jobs/procureme…

My lab Caltech Chemistry & Chemical Engineering is #hiring! Looking for a postdoc to join us in sunny Pasadena and tackle questions related to IDPs, phase separation, and transcriptional control in the context of physiology and disease. Please RT. Details and how to apply: jobrxiv.org/job/california…

Congratulations #UWMadisonChem Affilitate Assistant Professor Amy Weeks on becoming the 2024 @OnoPharmaFound Breakthrough Science Initiative Grant awardee. loom.ly/HaB7QvQ

UCSB to lead $22M NSF-funded center on exceptional microbes news.ucsb.edu/2024/021593/uc…

"A New Approach to Building 3-D Molecules for Better Drugs" loom.ly/rpA7ZPU Weix Group. This new report in Science from researchers at #UWMadisonChem represents a significant advancement in making the types of molecules needed in drug development.

We are excited to share our lab’s first research article! rdcu.be/dU5AC We have developed Transferrin Receptor Targeting Chimeras (TransTACs), a novel class of heterobispecific antibodies designed for targeted degradation of membrane proteins. nature.com/articles/s4158…

A team of researchers led by Wenjun Zhang reported the discovery of the first natural enzyme capable of creating complex molecules, azides, from simpler molecules 🧪 Read the story below 🔗 chemistry.berkeley.edu/news/first-nat…