Here’s a reframe. AI doesn’t take your job. AI allows you to do any job. So a coder can now make films. And a filmmaker can now write code. It allows a non-specialist to get started. But a specialist will be needed for polish.

A big question in software is what happens to the systems of record in a world of AI Agents. Do they go away? Do they just become databases? Or do they become more powerful? I’d argue that they’re just as powerful as ever, if not more powerful, in a world of 100X more

Extend Andrej Karpathy’s point that LLMs have properties of utilities These properties will flow downstream to fully autonomous services. Picture telemedicine run by AI: consistent quality, always on, almost free.

Of all the regrets of great founders, one of the most common I hear is allowing themselves to be taken out of the interview loop for all candidates too early. Christina says she should have waited until the third intervention from her team begging her to stop before she did 🤗

Reinforcement Learning in English – Prompt Learning Beyond just Optimization Andrej Karpathy tweeted something this week that I think many of us have been feeling: the resurgence of RL is great, but it’s missing the big picture. We believe that the industry chasing traditional RL is

To get better at thinking you need to think about how you think

Experienced founders are starting with forward-deployed engineers because SaaS is so easy to build, your best shot at defensibility is building exactly what smart companies need as quickly as possible The depth of your relationship with each customer matters more than ever

Just released gpt-oss: state-of-the-art open-weight language models that deliver strong real-world performance. Runs locally on a laptop!

She’s deaf so she’s not afraid of a firecracker… first time I’m smiling for a deaf dog

The AI opportunity in US healthcare in one simple chart.

Excited to share that we've raised a $22.5m Series A for Hello Patient, led by Scale Venture Partners. This is by far the worst announcement video I've ever made. I can't believe our lead investor agreed to this

High slope people are *so* different every year. It’s a good reminder to not freeze people in time

People leaving regular companies: Time for a change! Excited for my next chapter! People leaving AI companies: I have gazed into the endless night and there are shapes out there. We must be kind to one another. I am moving on to study philosophy.

🚀 It’s launch day! 🚀 The tasteandtactics podcast is finally live! Our first episode is with Jaclyn Pascocello, Founder of Fabrik, a network of member-based community & social spaces to help solve the $460B loneliness crisis.