NCCR RNA & Disease
@nccr_rnadisease
Swiss National Center of Competence in Research (NCCR): The role of RNA in disease mechanisms. Propelling research
forward since 2014. @snsf_ch @unibern @ETH
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https://nccr-rna-and-disease.ch/ 24-01-2019 18:06:42
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Review by the Polacek Lab (DCBPunibern, Universität Bern) w/ 1st author Robert Rauscher "Ribosomal RNA expansion segments and their role in ribosome biology" Biochemical Society Transactions bit.ly/3y4E94u
Preprint Gatfield lab,The Ban Lab& Teleman Lab w/ 1st author Romane Meurs "An in vitro assay of MCTS1-DENR-dependent re-initiation & ribosome profiling uncover the activity of MCTS2 and distinct function of eIF2D" bit.ly/4bPA9mg Adrian Bothe Center for Integrative Genomics, UNIL (CH) Université de Lausanne ETH Zurich DKFZ
Preprint by the Isabelle M Mansuy lab w/ 1st author Maria Dimitriu "NanoTag - an IgG-free method for mapping DNA-protein interactions" bioRxiv doi.org/10.1101/2024.0… Rodrigo Arzate-Mejía Leonard Steg Pierre-Luc Germain
Paperby@ProfVolkerThiel (IVI_Switzerland,Universität Bern)&Martin Beer labs (Friedrich-Loeffler-Institut)&Rocketvax"A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications"Nature Microbiology bit.ly/3Adi8RF
Wrapping up and closing the Stutz lab with a celebration! Our latest publication on our favorite budding yeast is now in Nucleic Acids Res. Check it out if you're into yeast genetics and DNA repair! Huge congrats to Audrey Noireterre, Julien Soudet and Ivona! academic.oup.com/nar/article/do…
Today is August 1st – and it's also #WorldRNADay! 🧬💉 Discover how a tiny #RNA molecule can treat #SpinalMuscularAtrophy, a hereditary disease in children, in the new interactive explanatory video #flashMOOC #unibern: sohub.io/top1. NCCR RNA & Disease Faculty of Medicine, University of Bern
Happy International #RNADay & Swiss National Holiday! On this occasion, we are happy to release the Flash MOOC on RNA - The Future of Medicine feat. Adrian Krainer & Oliver Mühlemann as experts! youtube.com/watch?v=VYtKSU… Thanks a lot to the iLUB team of Universität Bern! #RNA #SMA #ASO
1/ Preprint alert📢: Uncoupling the functional roles of Coronavirus Nsp1 biorxiv.org/cgi/content/sh… #biorxiv_molbio Doubly excited because this work is based on our first Master's student to graduate from the lab, Emilie Bäumlin. Universität Bern DCBPunibern MCID Bern NCCR RNA & Disease
Paper by the Leidel & Sebastian Glatt labs w/ 1st authors Ting-Yu Lin & Leon Kleemann "The molecular basis of #tRNA selectivity by human pseudouridine synthase 3" Molecular Cell bit.ly/4fFi9hO #RNA #Disease #CryoEM DCBPunibern Universität Bern Malopolska Centre of Biotechnology UJ Uniwersytet Jagielloński
Paper MZavolan(Lab) w/1st authors Arka Banerjee, Meric Ataman & Maciej Smialek"Ribosomal protein RPL39L is an efficiency factor in the cotranslational folding of a subset of proteins with alpha helical domains"Nucleic Acids Res bit.ly/3SIPaQb Biozentrum, University of Basel University of Basel
Having a hard time with #CRISPR HDR? Your cells might be fighting against you! TREX1 nuclease, high in some cells, eats up HDR donor templates. Check out our paper in Nature Biotechnology for the story & ways to improve HDR. nature.com/articles/s4158… With Erman KARASU & John Maciejowski
Preprint by the Karousis lab (Karousis Lab, DCBPunibern, Universität Bern) w/ 1st author Emilie Bäumlin "Uncoupling the functional roles of #Coronavirus #Nsp1" doi.org/10.1101/2024.0… bioRxiv #RNA #SARSCoV2
The "protein factories" of the cell, the ribosomes, consist of up to 80 components. MZavolan(Lab) and The Spang Lab discovered that a specific ribosomal component is crucial for embryonic stem cells to differentiate into diverse cell types. Nucleic Acids Res Swiss National Science Foundation biozentrum.unibas.ch/news/detail/ri…
In our new study we reveal how NAC coordinates and regulates successive co-translational nascent chain ⛓️ processing on the mammalian ribosome out today in nature rdcu.be/dRAQY collab with Deuerling Lab Shu-ou Shan Caltech Swiss National Science Foundation European Research Council (ERC) ETH Zurich
This afternoon the 5th NCCR RNA & Disease Summer School on "RNA Heterogeneity in Chemistry, Space and Time" kicked off in Saas-Fee, Switzerland, organized by Maria Hondele , Mühlemann Lab, Franka Voigt & Norbert Polacek Universität Bern Swiss National Science Foundation , Grosshans Lab
📽️ G&D Tapes 📽️ G&D author Josip Ahel tells us about a novel protein complex ChAHP2, which along with the ChAHP complex, plays a key role in retrotransposon silencing. Marc Bühler Read the full story #OpenAccess here: ➡️ tinyurl.com/gd351769
Thrilled to announce that Prof. Michael N. Hall Biozentrum, University of Basel University of Basel has been awarded the 2024 BalzanPrize for Biological Mechanisms of Ageing. Congratulations to Michael Hall and the three other prize winners! biozentrum.unibas.ch/news/detail/ba…