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A Structural Mechanism for Noncanonical GPCRSignal Transduction in the Hedgehog Pathway biorxiv.org/cgi/content/sh… #biorxiv_biochem

Very interesting mechanism for phosphorylation to block GPCR-G protein interactions. Nice work Schafer_Lab!

Congratulations to Dr. Minna Roh-Johnson (@roh_johnson_lab) for receiving an award from National Cancer Institute for excellence in diversity and mentorship! This honor supports her groundbreaking research and commitment to inclusivity in science. bit.ly/3O9KfoK

The Robertson lab has multiple openings for postdocs! Particularly interested in those with experience in either plate reader assays or ML, but all are welcome!; come learn about GPCRs, cryoEM, MD/FEP, drug discovery and more! jobs.bcm.edu/job/Postdoctor…

How cool is this - so many possibilities with this clever trick.

Happy New Year. I’m pleased to report publication of the Ducker lab’s latest cancer metabolism paper led by graduate student Kyle Dunlap in Cell Reports. cell.com/cell-reports/f… Thanks to U of Utah Dept of Biochemistry! Full thread and other site

Proud to share our work by a fantastic team, spear-headed by PhD student Tommy Sroka with major contributions by #xenopus expert Kerstin Feistel. We developed an improved iAPEX-based #ProximityLabeling method for #massspec based subcellular #proteomics. biorxiv.org/content/10.110…

“My advice is to take as much time as you can with on-the-job training,” says HHMI Investigator Nels Elde. “That's how you find out if you become a basic scientist.” Learn more about Elde’s lab at University of Utah: hhmi.org/news/evolution…

This is a really fascinating and important paper, on the mechanism of neurodegeneration in Huntington's disease. I often think single-cell 'omics is an overhyped approach, but it was completely essential here. 1/

Pursuing a PhD Is a Choice—And a Privileged One First and foremost, pursuing a PhD is a path we choose. No one is forced into it. There are plenty of career opportunities that do not require a PhD, and many of them offer stability, competitive salaries, and clear professional

NIH cuts are hitting young scientists the hardest. By David Baker. timmermanreport.com/2025/03/david-…

Our lab's first paper (w Neil Kelleher) is officially online at Analytical Chem today!! ACS Analytical Chemistry Journals Excited for the opportunities this work brings to profiling heterogeneous membrane proteins like GPCRs. Department of Biochemistry and Molecular Genetics CU Pharmacology CU Pharmacy BioFrontiers 💻🦠🧬🧪🧫💉📊📓 pubs.acs.org/doi/full/10.10…

Excited to see our new article is out in J. Am. Chem. Soc., comparing conformational equilibria of a human GPCR in lipid vesicles, nanodiscs, and detergents. Great work from students Arka Ray and Beining (Kim) Jin! pubs.acs.org/doi/10.1021/ja… #NMR #NMRchat

What keeps cancer cells in check—and can we tame hem? In 2 collaborative preprints, we trace glioblastoma cell transitions in space and decode what regulates their plasticity 🧠👇 📍 Spatial & multi-omic atlas: biorxiv.org/content/10.110… 📍 Regulatory logic: biorxiv.org/content/10.110…

Our recent take on localized #GPCR signaling Nina Tsvetanova Miriam Stoeber @bradenlobingier nature.com/articles/s4158…

Microbiomes shape our biology from gut-brain, skin, immunology, and more. Here, Rebecka Sepela et al explores octopus “taste by touch” sensation to ask how environmental microbiomes drive animal behavior. Cell Press, MCB_Harvard, Marine Biological Laboratory (MBL) cell.com/cell/fulltext/…