Very nice to see the work between MuscleX_Lab at Illinois Tech and RegnierLab F Moussavi-Harami, MD at University of Washington finally published in Journal of General Physiology. It has been a very long and productive collaboration and more papers in the making!!!

Here is a great opportunity for a PhD in Muscle Biophysics/Physiology in London Physiology at KCL School of Basic & Medical Biosciences kcl-mrcdtp.com/project/myosin…

Job opportunity: MuscleX_Lab's Weikang Ma and myself over Accelerated Muscle Biotechnologies are looking to create an "industry postdoc" position. Part time work for IIT/BioCAT and part time work for AMB. All publishable research science with potential of independent research. DM us if interested!

Calcium has a direct effect on thick filament activation in porcine myocardium, say Saffie Mohran, Weikang Ma MuscleX_Lab Illinois Tech and colleagues F Moussavi-Harami, MD RegnierLab UW Center for Translational Muscle Research UW Bioengineering: hubs.la/Q02QLwmL0 #CellMotility #Myofilaments #CardiacMuscle

Thick filament structural changes in the presence of calcium. From Saffie Mohran, Weikang Ma & colleagues MuscleX_Lab Illinois Tech showing that calcium has a direct effect on thick filament activation in porcine myocardium: hubs.la/Q02QLtSp0 #Myofilaments #CardiacMuscle

Kyrah L. Turner (WSU School of Biological Sciences) et al. discovered that the structural and functional effects of myosin regulatory light chain #phosphorylation are amplified by increases in sarcomere length and [Ca2+] 💡 📜Read the #Research here: buff.ly/3zG9DPr

We are glad to share that we got all the beam we expected from the new Advanced Photon Source into our experimental hutch, ~4 × 10^13 photons/sec at 250um ×250 um unfocused. We expect to welcome users back in the near future after the scientific commissioning.

First decoration at the new Fulton Lab

Congrats Vivek Jani well deserved

Very nice to see this project in the press!

Very productive run at Cornell High Energy Synchrotron Source with Vivek Jani and Marcus. We collect patterns from human heart tissue (HFpEF, HFrEF, HCM, SVD) probably for the first time ever there, and more patterns from animal hearts. Looking forward to come back soon!!!

A definition of a long haul. Very glad to see this one came through after years of work.

It was very nice to welcome our muscle users Anthony Hessel, PhD Michel Kühn Vivek Jani back after two years for Advanced Photon Source upgrade. BioCAT remains the state-of-art facility for muscle X-ray diffraction. Proposal for next run due in two days!

The PI of BioCAT, Thomas Irving, will give a talk today at 3:15-4:30pm CST titled “30 years of Muscle Diffraction at BioCAT - What have we learned about muscle contraction?” Welcome to join iit-edu.zoom.us/j/89428128891?…

The “sound” of the heart beats!

Excited to share BioCAT P30 grant received an outstanding overall impact score of 16! Grateful that the Fiber Core, which I lead, earned a perfect score of 10—a testament to the incredible work of our team and user community. We look forward to serve the field in the years ahead.

Our symposium is just around the corner—don’t forget to register to receive the Zoom link for the event. We look forward to seeing you there. iit-edu.zoom.us/meeting/regist… musclexlab.com/musclex-sympos…

#OPENACCESS: A higher ATP concentration turns thick myosin filaments into an ON state, leading to altered cross-bridge kinetics. These X-ray data correlate low ATP levels to the inactivated myosin state observed in certain heart diseases. buff.ly/6ZpKw3J