Will genomics widen or help heal the schism between medicine and public health? Via American Journal of Preventive Medicine (AJPM) sciencedirect.com/science/articl…

Integrating public health and health care: Protecting health is a team sport. Yet medicine and public health have been siloed for too long! Via NEJM nejm.org/doi/full/10.10…

In spite of the importance of gene-environment interaction in disease etiology and pathogenesis, its study has been surprisingly difficult to operationalize. An insightful review on the many roads to gene-environment interaction. Via AJHG cell.com/ajhg/fulltext/…

Check out our new weekly update of news and publications on the impact of genomics and precision health technologies on population health. #PHGKB phgkb.cdc.gov/PHGKB/phgHome.…

Are there effective strategies to improve implementation of cascade testing in hereditary cancer syndromes? A npj Journals Genomic Medicine systematic review. #tier1 nature.com/articles/s4152…

Cascade testing in relatives of Lynch syndrome patients is recommended, yet uptake is limited due to multilevel barriers that can disproportionately impact underserved populations in the United States. link.springer.com/article/10.100…

Progress and call to action for advancing access to genome sequencing for individuals and families with rare genetic disorders. Via npj Journals Genomic Medicine. nature.com/articles/s4152…

Knowledge of the contribution of somatic and germline mutations to human diseases has progressed significantly in recent years. This has led to several therapeutic treatments for cancer and monogenic diseases. Nature Reviews Genetics informative review. nature.com/articles/s4157…

Join us on May 22 during annual Public Health Genetics and Genomics week for a webinar on Emerging Opportunities for Genomics to Improve Population Health: Lessons learned from the National Academies Roundtable on Genomics and Precision Health. cdc.gov/genomics/event…

A UK Biobank study shows that males and females with C282Y homozygosity in the HFE gene have excess morbidity and mortality including those with undiagnosed hemochromatosis. What are implications for clinical practice and population screening ? #tier1
bmjopen.bmj.com/content/14/3/e…

People with European genetic ancestry represent only a minority of the world’s population, yet they account for more than 90% of participants in large genomics studies. Via JAMA AllofUsResearch jamanetwork.com/journals/jama/…

The AllofUsResearch program releases almost a quarter of million clinical grade genome sequences in a uniquely diverse population: What have we learned so far on the role of genomics in health and disease? Via nature nature.com/articles/s4158…

Optimizing the use of 10 chronic disease polygenic risk scores to accelerate implementation in clinical practice in diverse populations. Via Nature Medicine nature.com/articles/s4159…

An informative scoping review on the publics knowledge, attitude and motivation towards health-related applications of genomics. Via European Journal of Human Genetics nature.com/articles/s4143…

The emergence of gene therapy for sickle cell disease: An informative review. ashpublications.org/blood/article/…

Genetic testing for Familial Hypercholesterolemia: Where are we? An informative review. journals.lww.com/co-lipidology/…

Using implementation science to evaluate a population-wide genomic screening program in South Carolina. Via AJHG cell.com/ajhg/fulltext/…

A new roadmap for reducing the global burden of Familial Hypercholesterolemia from the International Atherosclerosis Society. #tier1 #knowFH #findFH globalheartjournal.com/articles/10.53…