What can I say? 🏆🥹 Roland-Garros 📸 Getty

Second tumors after CAR T-cell therapy are rare, and in one case of a secondary T-cell lymphoma, detailed analysis showed that the genetic construct that was used to make the CAR T cells was unrelated to the second tumor. Read the full study results: nej.md/3Rln392

ASXL1/TET2 genotype-based risk stratification outperforms ASXL1 mutational impact and is independent of mutant variant allele fractions Clifford Csizmar Eric Padron MD Guillermo Montalban-Bravo Rami komrokji #CMML #TET2 #ASXL1TET2 Haematologica pubmed.ncbi.nlm.nih.gov/38899337/

Two papers in nature present a new genome editing technique that enables the insertion, inversion and deletion of long DNA sequences at user-specified genome positions. The approach may provide an easier method of genome editing. go.nature.com/3RGkI8M go.nature.com/3RHBvIs

Next up at #iwMPN24 Mrinal Patnaik (Mayo Clinic Comprehensive Cancer Center) talks on RASopathies, key features of RAS family-mutated chronic myelomonocytic leukemia and treatment options VJHemOnc #iwMDS24 #iwMPN24 #MPN #MPNsm #CMML

He came, he saw, he conquered 🫡 Rohit Sharma plants his flag into the history books 🇮🇳

Hair follicle DNA extraction for germline testing in hematologic malignancies improves process efficiency, patient care and reduces costs, allowing for quicker treatment decision-making. Mayo Clinic hematologist-oncologist Dr. @mrinalpatnaik explains how: mayocl.in/45Mge6k

Hair follicle DNA extraction for germline testing in hematologic malignancies improves process efficiency, patient care and reduces costs, allowing for quicker treatment decision-making. Mayo Clinic hematologist-oncologist Dr. @mrinalpatnaik explains how: mayocl.in/3RZJMrI

Mayo Clinic Telomere Biology Disorders Group #Telomeres Team Telomere Mayo Clinic Center for Individualized Medicine Alex Ferrer Terra Lasho, PhD Doug Simonetto, MD Mayo Clinic Comprehensive Cancer Center Kristen McCullough MayoPCCM Dr Eva Carmina Dr Anna Zamora

Genentech published a sequencing comparison of all commercial single-cell technologies two weeks ago. Fluent offers a low cost per cell but has a long way to match 10x in sensitivity. ILMN could go for 10x/Parse, probably didn’t want to upset their friends at the FTC..again

Clonal Hematopoiesis in Patients With Neuroendocrine Tumor Treated With Lutetium-177 and the Risk of Thrombocytopenia … pubmed.ncbi.nlm.nih.gov/38976813/ yael kusne MD PhD Terra Lasho, PhD #Lutetium #CH #Radiotheranostics Mayo Clinic Comprehensive Cancer Center

How DNA guides cancer detection | Tomorrow's Cure Episode 3 youtu.be/x7CjqdQDSbg?si… via YouTube Mayo Clinic Comprehensive Cancer Center Kelly Bolton MD PhD #Cancergenomics

When you get an opportunity to write #CMML diagnostic criteria for the World Health Organization (WHO) with the dream team. Eric Padron MD Raphael Itzykson Joseph D. Khoury, MD, FCAP #Ericsolary Mayo Clinic Comprehensive Cancer Center Moffitt Cancer Center

Absence of PNH-clones in DDX41mutant-GPS aids in their distinction from acquired bone marrow failure syndromes ... sciencedirect.com/science/articl… yael kusne MD PhD Tim Chlon Talha Badar Mayo Clinic Comprehensive Cancer Center #DDX41 #Bonemarrowfailure

Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program | Science science.org/doi/10.1126/sc…

#MPNWorkshopNC | Mrinal Patnaik of Mayo Clinic is first up in the session on rare & overlap syndromes with his talk, 'Novel Therapeutic Targets in CMML'. This is sure to be an interesting session!👏 Atrium Health South Piedmont AHEC #MPNsm #HemOnc

Now online in Cancer Discovery: RNA shielding of p65 Is Required to Potentiate Oncogenic Inflammation in TET2-mutated #ClonalHematopoiesis - by Nana Adjoa Ben-Crentsil, Alexandre Gaspar Maia Mrinal Patnaik Eric Padron MD and colleagues doi.org/10.1158/2159-8… Mayo Clinic Moffitt Cancer Center

RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis. pubmed.ncbi.nlm.nih.gov/39189614/ Our latest collaboration with Eric Padron MD Alexandre Gaspar Maia #TET2 #MALAT1 #CH Mayo Clinic Comprehensive Cancer Center Moffitt Cancer Center Cancer Discovery

Acute kidney injury, an underrecognized feature of VEXAS syndrome. pubmed.ncbi.nlm.nih.gov/39186250/ #VEXAS #Kidney Mayo Clinic Comprehensive Cancer Center KenWarringtonMD

An ancient gene gives spiders their teeny waistlines | Science | AAAS science.org/content/articl…