Excited to share our latest collaboration with Martijn Luijsterburg. We characterize a new XPA patient allele that weakens the interaction with TFIIH and selectively affects TC-NER. Congratulations to Mihyun Kim and all authors. pnas.org/doi/epdf/10.10…

So happy to take our group photo with cherry blossoms 🌸

How telomeric replication stress leads to telomere breakage initiating break-induced replication (BIR) in alternative lengthening of telomeres (ALT)? We identified the polyUb-PCNA-SLX4 axis as an endogenous trigger for directing BIR. Please check here 👉doi.org/10.1101/2023.0…

Please check out our latest review discussing our obsession with how protein-protein interactions guide the nucleotide excision repair pathway with Areetha D'Souza, Mihyun Kim and Walter Chazin. Hope you will find it informative! sciencedirect.com/science/articl…

Food and art day at the lab