The The RNA Society's RNA Salon program supports recurring local RNA science-based activities throughout the world. We are now inviting applications for RNA Salons in 2024/25! Applications must be submitted by August 31, 2024. For more details: rnasociety.org/salons @Lexogen

In our new paper aided by single molecule imaging of RNA and transcription machinery we demonstrate how Polycomb Repressive Complex (PRC) represses transcription in live cells 🧵 nature.com/articles/s4155… 1/9

🚨 17 PhD positions available, including 2 in Leicester, to work on different aspects of insect biology as part of the MSCA-DN INCITE project! 🐞🔬 Interested? Apply now and help spread the word! researchjobs.cz/job/europe-17-…

Really excited to share my preprint describing a novel activation mechanism of CDK12/13 by the PAF1 complex essential for transcription elongation! biorxiv.org/content/10.110…

I am happy to share our latest paper with Gilbert Ansa and Shona Murphy in which we show that two small molecule inhibitors of RNA splicing, Isoginkgetin and Madrasin, do not directly inhibit RNA splicing but rather strongly affect transcription activity. journals.plos.org/plosone/articl…

🚨New Review🚨 We've recently seen huge advances in our understanding of de novo DNA methyltransferase function. Willow Rolls and Marcus D Wilson and I have written a mini-review on what human disease mutations told us: doi.org/10.1042/BST202… #Epigenetics #Epigenomics 🧵 1/2

Scientific research needs robust government backing, not Treasury penny-pinching | Andre Geim and Nancy Rothwell | The Guardian theguardian.com/commentisfree/…

How are promoter interactions coordinated during cell differentiation? In our first paper, we investigate the temporal relationship between genome folding, transcription and histone modifications during ESC differentiation. (1)

Our latest work—and our first effort to understand the sensory system in mosquitoes! 🦟 royalsocietypublishing.org/doi/10.1098/rs…

🤩10th Dec 🗓️ we'll have the pleasure of discovering the work of M. S. Luijsterbug Martijn Luijsterburg, E. Belotti Edwige Belotti and M. Tellier Michael Tellier. We'll see how RNAPII is regulated at UV damage sites, during replication and how H2A.Z protects the genome integrity.

What happens when you overexpress one subunit of the RNA Pol II? Well, it depends on the subunit, but all deregulate transcription and induce genome instability Aga Gambus Lea Haarup Gregersen biorxiv.org/content/10.110…

🚨Our next EDRA webinar is coming up. We will have the pleasure of discovering the work Martijn Luijsterburg, Edwige Belotti and Michael Tellier. If you're a fan of Transcription, Replication, Aging and DNA Repair... See you on 10th Dec 🙂

Interested in RNA biology, cancer or vascular research? I have a position open for either a research assistant or a new postdoc to start expanding the fast-growing research area of cardio-oncology! Apply here: jobs.ncl.ac.uk/job/Newcastle-… Happy to have informal chats! Please share 🧬.

Thank you to Martijn Luijsterburg, Edwige Belotti, and Michael Tellier for sharing your fascinating research and delivering fantastic talks! 🌟 Your insights into RNAPII regulation and H2A.Z’s role in genome integrity were truly inspiring. We look forward to seeing you next year.

Recruitment news! Still time to apply to one of our Medical Research Council funded 4 year PhD studentships. Studentships available at University of Leicester Uni of Nottingham #WeAreUoN and Uni of Birmingham 📅Deadline midday (GMT) Friday 10 Jan 2025. All details more.bham.ac.uk/mrc-aim/phd-op…

Our letter-to-the-editor providing evidence that ARK2N is not a core factor in transcription-coupled DNA repair is now online in PNAS! Well done Janne van Schie and Sem Brussee. pnas.org/doi/10.1073/pn…

We showed Pol II stability is regulated by SPT5/Cullin 3 bit.ly/4hoNMN7 Dr. Yuki Aoi, Leila Iravani & team just published & identified ARMC5 as a specific adaptor certifying elongation competent Pol IIs & making sure “bad” enzymes are eliminated! bit.ly/4jx9UWP

We are recruiting! Center for Gene Expression has 2 or more open positions for PhDs University of Copenhagen. Come join our team to work on RNAPII and transcriptional regulation (gregersenlab.com) Great city and amazing research environment. Deadline March 6 jobportal.ku.dk/phd/?show=1634…

Save the date! On March 25th, We'll dive into Nanofluidic tools for studying DNA repair with Fredrik Westerlund @FWesterlundand and R-loops & genome instability with Sidrit Uruci Sidrit Uruci (Sid) & Agnese Cristini Agnese Cristini.