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#IntrinsicallyDisorderedProteins in the center of the pore of the nuclear envelope can form spaghetti-like barrier permeable for cellular factors but blocking viruses and pathogens press.uni-mainz.de/how-wiggly-spa… #biophysics Lemke Lab IMB Mainz SFB 1551 - Sonderforschungsbereich 1551 SPP2191 - Mol. Mech. of Funct. Phase Separation Max Planck Institute of Biophysics Hummer Lab nature

Scientists at IMB, Universität Mainz & Max Planck Institute of Biophysics showed how #IDPs in the centre of the #NuclearPore form a spaghetti-like mobile barrier that allows important cellular factors to pass but blocks viruses & molecules that can cause disease. #condensate #biophysics 📰imb.de/about-imb/news…

Emmm...I have a question: We used light to study dark proteins. That makes us The Dark Side or The Light Side???!😅 #StarWars

#MayThe4thBeWithYou Doing science can be full of fun! This is the way!😆🤗🤓

I had a lovely visit to Abberior in Heidelberg and tried my favourite protein Nup98 with Minflux! The resolution is mind-blowing!🤯🤩 I asked Clara how often they meet with Stefan Hell here. She said roughly once per month. AND then Stefan just came in! I was super excited!😇

We are looking for Postdoc applicants with a strong interest in further expanding quantitative single molecule technologies to understand the molecular mechanisms of IDPs within cells Mainz University IMB Mainz nature.com/naturecareers/…

Captured a nostalgic moment on my last day at Lemke Lab-a snapshot with my trusty microscope. Grateful for an enriching 5-year postdoc journey alongside my mentor, Edward, the best PI, and the most incredible colleagues. These memories will always have a special place in my heart

Thrilled to announce my new role as a Professor of Cell Biology at Wuhan University Wuhan University! My lab will delve into the dynamic world of intrinsically disordered proteins in live cells, utilizing interdisciplinary tools to unravel their functions. Excited for the journey ahead!

Embracing the Year of Dragon's spirit, we've adorned our lab door with Spring Festival Couplets: 神龙舞光影无序，显微成像探玄奇. Translated, the divine dragon dances, casting 'disordered' shadows of light; meanwhile, microscopic imaging unveils the profound mysteries within 🐉🎊

🎓The Hongyi Postdoctoral Fellowship at #WHU is now open for application! 💪We offer research support, education subsidies, housing and medical coverage aside from a salary package. ‼️Submit your application before the end of September. For more info: brnw.ch/21wHsNk

Lovely gift from my students!🥰😊 Happy #InternationalWomansDay!! #newPI #WomenInSTEM

Happy to meet friends at IDP GRC in Les Diablerets. We hiked to see the water fall, and suddenly water started to fall...😅

Check out this "Voices" article in Cell Press which highlights our former group member, Miao Yu's research and career!

🙋🏻🔬 Will you be joining us for #EMBOinsitu? What are the recent methodological developments and new tools for cell biology across scales: from molecules to organelles, cells and cell-cell interactions❓ How does one meaningfully integrate data from different methods❓ What

📢 Deadline extension alert! In case you missed it, you now have one more week to submit your abstract for 'In situ structural biology: expanding the toolbox for structural cell biology'❗ #EMBOinsitu 🔬 From cryo-EM to multi-scale modelling – what types of biological questions

Thrilled to share our latest paper in @PNAS! We enhanced SAXS with noncanonical amino acid labels to extract both RG and RE of IDPs, addressing key discrepancies in biophysical measurements. Big thanks to Lemke Lab for the amazing ASAXS-inspired T-shirt! pnas.org/doi/10.1073/pn…

Protein clumps in the brain are tied to neurodegenerative diseases, but measuring them is difficult. EMBL Hamburg's #SAXS experts & Lemke Lab developed a technique to measure clumping with anomalous X-ray scattering in solution. embl.org/news/science-t…

🚨New Review Alert!🚨How do disordered FG-Nups regulate nuclear transport?🍝 Our latest review explores recent advances in imaging & modeling, linking NPC function to disease. 👉portlandpress.com/biochemsoctran…