Can scientists be taught how to choose good projects? I took a fantastic class taught by Michael Fischbach last quarter where the foundational hypothesis is: Yes, they can! And I continually come back to these core insights as I think about project choice and direction in my 2nd year of

Many small neuroimaging studies have probably reported false positive findings. Especially for traits related to cognition & mental health, thousands of subjects are required 🧠 New paper from our talented PhD student Shu Liu in Nature Human Behaviour: nature.com/articles/s4156…

Your academic CV is NOT linked to your ability to make big discoveries. ▫️ 1. Andre Geim, a co-discoverer of graphene, wrote in his Nobel Lecture article: - “So, at the age of 33 and with an h index of 1 (latest papers not yet published), I entered the Western job market for

Our new study is out today in Nature! We demonstrate a brain-computer interface that turns speech-related neural activity into text, enabling a person with paralysis to communicate at 62 words per minute - 3.4 times faster than prior work. 1/3 nature.com/articles/s4158…

Published ahead of print: In this retrospective cohort study, the authors present characteristics, histological subtypes and outcomes of adult central nervous system #tumours in 501 patients. Read more: journals.lww.com/smj/fulltext/9… Mervyn Lim #Neurosurgery

Identifying a potential novel DBS target for cognitive impairment in Parkinson’s disease. Nice study in Brain and accompanying very nice commentary by Prof. Vladimir Litvak find me @vlitvak.bsky.social and Hnaznae 'Uncovered caudate and DLPFC biomarkers for use with closed-loop strategies. As the technology

How likely are #young #stroke survivors to return to work? We explore this in both #ischemic and #haemorrhagic stroke. Mervyn Lim Ching-Hui SIA leonard yeo sciencedirect.com/science/articl…

A research collaboration led by Mervyn Lim showed that trends in Hemorrhagic stroke are evolving in Singapore. Hemorrhagic stroke incidence increased significantly in younger people <65yo. Read more here: journals.sagepub.com/doi/10.1177/23… #youngstroke Ching-Hui SIA

We report that a substantial proportion of MMD patients have #cognitive #impairment. Prevalence and Associations of Cognitive Impairment in Adult Patients with #Moyamoya Disease in the Journal of Alzheimer's Disease. Ching-Hui SIA leonard yeo Mervyn Lim StroCar: elucidating heart-brain interactions content.iospress.com/articles/journ…

Wow, with the new UK Biobank rules, the dataset has just become way too expensive for the kind of computationally intensive work my lab does...

There's a viral video going around about an MIT neurosurgeon who quit to spend time alone in the mountains. It's such a great perspective on our broken healthcare system (and getting healthy) that I thought I'd share the key excerpt here:

The impact of frailty on stroke outcomes is increasingly being recognised. In our study led by Mervyn Lim, we show in a cohort of 1223 spontaneous ICH patients that frailty was associated with mortality and poor functional outcomes. leonard yeo sciencedirect.com/science/articl…

#OnlineFirst: A taxonomy for cerebellar cavernous malformations: subtypes of cerebellar lesions. thejns.org/view/journals/….

Boom! Cerebrospinal fluid (CSF) flow extends to peripheral nerves. Alexander Ligocki, Ed Scott and colleagues FLORIDA UF Health blow our minds. New paper Science Advances. What will we call it now? Cerebro-spinal-nerve fluid (CSNF)? or maybe brain-spinal-nerve fluid (BSN)? Just when

Here's a preliminary release of our calculator to explore sample size and scan time to maximize individual-level prediction accuracy: leonoqr.github.io/ORSP_Calculato… Let us know if anything is unclear or if there's bugs. Your feedback is welcome. If you find this calculator helpful for

This paper is not that well cited, but still one of my favorite papers showing that resting-state correlations (aka functional connectivity) is biologically meaningful. (I am not an author)

Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies. The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% accuracy.🧵

📢Specialist healthcare professionals in neurology, neuro-oncology & surgery show positive attitudes toward advance care planning (ACP), but confidence in conducting ACP needs improvement. Training & support can bridge the gap! 🔗 Read more: journals.lww.com/smj/fulltext/9…