Maps and models for our work have been released by Protein Data Bank 16120/8BMP - ECF-FolT2 + ADP/ATP (MSP2N2) 16121/8BMQ - ECF-FolT2 + AMP-PNP (MSP2N2) 16122/8PMR - ECF module (MSP2N2) 16123 - ECF module (DDM) 16124/8BMS - ECF module 2EQ (MSP2N2) doi.org/10.1038/s41467…

Congratulations to Valeria and the rest of the team! It still feels like a piece of work that we can all be proud of in Groningen, where you spend so many hours optimizing expression, purification and data processing... even though all of you have moved on - sadly (!)

Solène is an artist, not only for cake decoration, but also in the lab!

Anna will be chairing the 2024 #Ligand Recognition and Molecular Gating GRS in Ventura, CA. Join her there, it will be amazing!

ECF transporters never fail to surprise. Michele found a new transceptor case: biorxiv.org/content/10.110… Happy holiday break!

What are the limiting factors of protein diffusion in bacteria periplasm and what influences it? We used single-protein displacement measurements and extensive computer simulations to give some answers on these question. doi.org/10.1016/j.jmb.… Done in Membrane Enzymology group

Congratulations to Ivan!

In very good tradition of celebrating beautiful data, the image has been stuck on my door for some time now!

Back from the GRC Ligand Recognition and Molecular Gating; sadly the chair Kaspar Locher could not be present but stand-ins Crina Crina Nimigean and Edmund @Mitocarriers saved the conference, together with the GRS chairs Anna and Franziska Anna Borowska Franziska Heydenreich. Thanks!

Single-molecule optical tweezers reveal salt dependence of the interdomain interactions in a membrane transporter OpuA in nanodiscs Congratulations to Lyan van der Sleen and all the authors! Jan Stevens Siewert-Jan Marrink Kasia Tych 👏Membrane Enzymology Cell Reports: doi.org/10.1016/j.celr…

Bacterial S-components have crossed the border between transporters and receptors doi.org/10.1038/s42003… Congratulations to Michele on finding this unexpected "transceptor" link

Congratulations Jose! Not only for the paper (doi.org/10.1016/j.str.…), but also for you successful defence of your thesis yesterday.

It took some time, but Anna’s Anna Borowska beautiful work on the exchange mechanism of ASCT2 is now out. Together with twitterless Gabriella and @CPaulino Alisa Garaeva Jan Rheinberger Siewert-Jan Marrink nature.com/articles/s4146…

Next level reconstitution: Combining the malate decarboxylation pathway with transporters (GltP, LacY) in liposomes, Miyer and Zaid generated stable proton and electrical potential gradients and accumulation of glutamate and lactose over periods of hours.nature.com/articles/s4146…

If you are interested in a joined effort towards building a synthetic cell (including -of course- membrane transporters), have a look at this post: nature.com/naturecareers/…