Michael Meinecke Lab
@meineckelab
We study #cellmembranes, integral membrane proteins and #mitochondria.
ID: 1225680454818258946
https://bzh.db-engine.de/group/81/michael%20meinecke 07-02-2020 07:19:55
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Excellent work of the past years by our incoming PostDoc beyenech binotti
Super interesting read from Itay Budin at The EMBO Journal. In case you wondered, yes lipids (#lipidtime) are important for mitochondrial inner membrane morphology. embopress.org/doi/full/10.15…
Our paper in Biophysical Journal is about lipids, obviously, but there's a neat little trick for the caged compound / photopharmacology / optogenetics crowd: A method for absolute quantification of single-cell photo reaction yields directly from reporter responses.
Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria: Molecular Cell cell.com/molecular-cell… Congratulations to the team for our new paper. Special thanks to collaborators Warscheid lab, Hauke Hillen, Ricarda Richter-Dennerlein
Delighted that our paper is out in CDD press with James, Richard Turkington & dlongley. We present a new regulatory role for the E3 Ub ligase Itch in apoptosis and mitochondrial cholesterol supply. rdcu.be/dvRnh The Patrick G Johnston Centre for Cancer Research #apoptosis #mitochondria #cholesterol #ubiquitin
Protein filaments inside mitochondria? Using STED, 4Pi-STORM, and EM, we show that the MIC10 orthologue from Drosophila can polymerize into cristae-shaping filaments! Happy to see our collaborative study published in Life Science Alliance. life-science-alliance.org/content/7/4/e2… JakobsLab
People of molecular biology! Please distribute: -Super exciting and hot topics, - Working with us 😁 in a great city of Warsaw - Generous EU funds 😊 Ministerstwo Nauki i Szkolnictwa Wyższego
Our latest submission to bioRxiv is now available online: biorxiv.org/content/10.110… A joint effort between Harpreet, Jutta, and Asen, and our previous rotation students Eric, Christian, David, Katalin, Daniel, and Felix Uni Heidelberg biorxiv_biochem DFG public | @[email protected]
More on bacterial ESCRT-III: a total 30 cryo-EM structures of Vipp1 organized in membrane-bound coats, carpets, ring complexes, stacked-ring assemblies, and helical tubes inducing high membrane curvature. Great collaboration with Dirk Schneider! biorxiv.org/content/10.110…