
McKinsey Lab
@mckinseylab
Cardiovascular disease and fibrosis research. Signaling and epigenetics. Colorado, teamwork, fun, and dedicated to making a difference. cfret.org
ID: 1359740396222308355
https://medschool.cuanschutz.edu/cardiology/research/basic-translational-research/mckinsey-lab 11-02-2021 05:46:00
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We are excited to share the launch of the new Cardiovascular, Renal, and Metabolism Center (CRMC), an initiative focused on advancing cardiovascular, kidney, and metabolic health. 🩺 Led by Srinivasan Beddhu, MD, and Stavros George Drakos. Learn more: medicine.utah.edu/internal-medic… #meded



Thank you AJP-Heart and Circ for publishing our recent work on BRD4 in cardiac macrophages. Huge effect on MHC-II levels. doi.org/10.1152/ajphea…. Great team effort and collaboration with many, including Ron Vagnozzi and Michael Alexanian.


Excited to share our latest paper in #EHJ, led by talented postdoc Yue Yuan (who is x-less). BCM_CVRI Prof. Dr. med. Dobromir Dobrev BCM Department of Medicine EHJ Editor-in-Chief European Society of Cardiology Journals Atrial cardiomyocyte-restricted cleavage of gasdermin D promotes atrial arrhythmogenesis academic.oup.com/eurheartj/arti…



Excited to share our latest article. 7 years ago my then 9 year old son was diagnosed with K210del DCM. With the help of my colleagues Joseph C Wu, MD, PhD, Sakthivel Sadayappan, PhD, MBA and Enzo Porrello we identified an FDA approved drug that corrects the mutation. JCI - An FDA-approved drug

Happy to share our paper, "Logic-based machine learning predicts how escitalopram (LexaPro) attenuates cardiomyocyte hypertrophy" in PNASNews, with Taylor Eggertsen with Josh Travers, McKinsey Lab, & Matthew J Wolf, MD, PhD. Validated in cells, mice & patients. pnas.org/doi/10.1073/pn…




#HFpEF Summit 2025 - another year, another success. Grateful for all speakers, attendees and sponsors! VCU Health Pauley Heart Center Smidt Heart Institute at Cedars-Sinai David Lefer


Our first foray into using AI to tackle human cardiac fibrosis. ahajournals.org/doi/full/10.11…. Amazing collaboration with Gregory Way and waysciencelab.com. Spearheaded by Josh Travers and Jenna Tomkinson. Tip of the iceberg. Stay tuned!


UAB at ISHR 2025: Fantastic science, amazing friends, beautiful location! UAB Heersink School of Medicine UAB Pathology UAB Cardiovascular Disease Wende Lab



Amazing Circulation Research Compendium on Interorgan Crosstalk, organized and edited by Maria Kontaridis and Gabriele G. Schiattarella. The potential to manipulate fat-heart crosstalk for therapeutic purposes is enormous. Check out our take! ahajournals.org/doi/full/10.11…



Congratulations to Dr Natalie Gehred on her AMAZING PhD defense: Cardiac Fibroblast Heterogeneity and Epigenomic Regulation in Heart Failure UCLA Anesthesiology UCLA MBI UCLA David Geffen School of Medicine at UCLA

