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SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy dlvr.it/RYJZSK

Elevated NSD3 histone methylation activity drives squamous cell lung cancer | Nature nature.com/articles/s4158…

Hyperactivity of the methyltransferase protein NSD3 drives some cancers go.nature.com/3rd90Tw

New work from Or Gozani Pawel K. Mazur and co. finds that a mutated form of NSD3 results in increased H3K36 methylation and promotes lung cancer development. Also used EpiCypher's pAG-MNase for CUT&RUN assays and our nucleosomes for HMT experiments! #chromatin nature.com/articles/s4158…

The discovery that methyltransferase protein NSD3 drives some cancers opens up new therapeutic opportunities go.nature.com/3rd90Tw

Researchers at Stanford University, MD Anderson Cancer Center, KAUST & University of Macau showed that elevated NSD3 histone methylation activity drives squamous cell #LungCancer. 📌 @nature 🔗 go.nature.com/3oKFNgV

Hyperactivity of the methyltransferase protein NSD3 drives some cancers go.nature.com/3rd90Tw

Trending on PubMed: Elevated NSD3 histone methylation activity drives squamous cell lung cancer. pubmed.ncbi.nlm.nih.gov/33536620/

Elevated NSD3 histone methylation activity drives squamous cell lung cancer disq.us/t/3umvu6p

#ResearchWatch: The histone methyltransferase NSD3 is a lung squamous cell carcinoma driver. Pawel K. Mazur MD Anderson Cancer Center Stanford University #LungCancer #Epigenetics bit.ly/3qxsTov

NEW #ResearchHighlight! Research by the teams of Shao, Jaremko, Mazur Pawel K. Mazur & Gozani shows that NSD3, which encodes a histone H3 lysine 36 methyltransferase, is likely an important driver of a subset of lung squamous cell carcinomas. 📯 go.nature.com/3qMIgcJ Cancer at Nature Portfolio

Excited about this publication from star student Andrea Chaikovsky Stanford Cancer Biology PhD Program on the regulation of Cyclin D levels and the response to Cdk4/6 inhibitors. Close collaboration with many labs, including Monte Winslow's Lab, Dmitri Petrov, Christina Curtis, Krogan Lab... rdcu.be/ciGW3

Happy Halloween from the Mazur Lab! #halloween2021

The Pawel K. Mazur at MD Anderson is wearing purple on #WorldPancreaticCancerDay to raise awareness for this devastating disease #PanCANawareness

The @Mazurlab walked to today to raise money and awareness for pancreatic cancer at the Purple Stride in Houston #PanCAN #PanCANPurpleStrideHouston

1/11 🧵 Our new paper in now live in Cancer Cell cell.com/cancer-cell/fu… You can explore our data through the interactive portal: singlecell.mdanderson.org/GastricTME/ MD Anderson Cancer Center #TumorMicroenvironment #Gastric Cancer #CAFs #SingleCell