
Matthew Gaunt
@matthewgaunt8
ID: 1013136188000079878
30-06-2018 19:04:25
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congratulations to the Joseph, Roopender Kumar, John, James, Nils and Sarah for their work on a broad amine synthesis platform. A pre-Covid project, this work is new take on an classic but under-appreciated problem. A lot of problems are solved here. pubs.acs.org/doi/10.1021/jaā¦

Here is our work on pyrimidine diversification with Robert Paton. This approach effectively allows you to exploit de novo heterocycle synthesis at the later stages of drug and agrochemical development. Congrats to Ben, Celena, and Louis! nature.com/articles/s4158ā¦

Great news: our group's first paper is out in ACIE! Thanks a lot to the team and our collaborators Kirchner Research Group , Schiemann, Kielb Groups. It was an incredible journey! A General IronāCatalyzed Decarboxylative Oxygenation of Aliphatic Carboxylic Acids onlinelibrary.wiley.com/doi/10.1002/anā¦

This might look like a reaction you think is well established, but itās not been possible before now. Hereās a modular and practical process to make these molecules in a single step. Great work by Alex, Roopender Kumar and Rachel thatās finally online. onlinelibrary.wiley.com/doi/10.1002/anā¦

A modular dual catalyst system enables tuneable alkene chloro-arylation to highly functionalized chloroalkanes. Congrats to Bo, Ala, Daniel, Katherine and Jean. Out now in Angewandte Chemie onlinelibrary.wiley.com/doi/10.1002/anā¦

Our Carbonyl Azinylative amination (CAzA) for the synthesis of α-heteroaryl amines is now out in Angewandte Chemie! Congrats Alex (Alex Rafaniello), Roopender (The Kumar Lab) and Rachel!š Read it here š onlinelibrary.wiley.com/doi/10.1002/anā¦


Hereās a new paper from our amine synthesis program. pubs.rsc.org/en/content/art⦠Led by Milo Smith and supported by Ryan Kang and Roopender Kumar, this works provides a mild way to make branched 2ā-alkylamines Follow Milo Smith as he moves onto his next adventure with Shenvi Lab

Hereās another contribution to our amine synthesis platform. A modular, practical and general carbonyl acylative amination to alpha-amino amides and ketones. Great work by Jianzhong Liu. Heās looking for academic positions and is definitely one to watch. pubs.acs.org/doi/10.1021/jaā¦

I will start my independent career at Texas Tech Texas Tech University in January 2025! (whitehurstlab.org) Thanks to my mentors Matthew Gaunt Paul Chirik Ritter Lab!



Hereās a straightforward and practical way to make heteroaryl substituted alkyl amines. Surprising how few methods generate this type of useful functionality. Great work by Alex (now at Dr Reddyās), Roopender Kumar (Assist. Prof at UCL) and Rachel (starting final year of PhD).

New from our photocatalytic multicomponent amine synthesis program. A mechanistically distinct method for the generation of unbiased a-amino radicals formed from iminium reduction. Great work by Harry, who solved some challenging problems in this project. pubs.acs.org/doi/10.1021/jaā¦

Come and join our team. We have an exciting Synthetic Chemistry PhD opportunity in the The Gaunt Group (starting Oct 2025) in collaboration with AstraZeneca. It will focus development of new catalytic activation modes for the synthesis of novel scaffolds. jobs.cam.ac.uk/job/48481/


Very excited to share our latest protocol in Nature Catalysis for photocatalytic generation of alkyl carbanions - no need organometallic reagents or reducing metals. Starting from alkene feedstocks, it works with diverse carbon electrophiles. š„ A Herculean effort led by


The The Gaunt Group are looking for two enthusiastic and talented researchers to join our dynamic team in Cambridge, as postdocs. If you are interested in developing cutting edge synthetic chemistry across a wide range of areas relating to catalysis, apply at jobs.cam.ac.uk/job/49113/

Happy to see our Carbonyl Azinylative Amination work by Alex, Roopender and Rachel forming diverse heteroarylaklyamines using in situ generated heteroarylindium species highlighted in ACS Publications OPR&Ds new items of interest! pubs.acs.org/doi/10.1021/acā¦



3-Selective Pyridine Fluorination via Zincke Imine Intermediates | Journal of the American Chemical Society Colorado State University Total Synthesis and Methodology Highlights pubs.acs.org/doi/10.1021/jaā¦