Matthew Gaunt (@matthewgaunt8) 's Twitter Profile
Matthew Gaunt

@matthewgaunt8

ID: 1013136188000079878

calendar_today30-06-2018 19:04:25

124 Tweet

1,1K Followers

72 Following

Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

congratulations to the Joseph, Roopender Kumar, John, James, Nils and Sarah for their work on a broad amine synthesis platform. A pre-Covid project, this work is new take on an classic but under-appreciated problem. A lot of problems are solved here. pubs.acs.org/doi/10.1021/ja…

Andy McNally (@andymcnally367) 's Twitter Profile Photo

Here is our work on pyrimidine diversification with Robert Paton. This approach effectively allows you to exploit de novo heterocycle synthesis at the later stages of drug and agrochemical development. Congrats to Ben, Celena, and Louis! nature.com/articles/s4158…

Bunescu Lab (@ala_bunescu) 's Twitter Profile Photo

Great news: our group's first paper is out in ACIE! Thanks a lot to the team and our collaborators Kirchner Research Group , Schiemann, Kielb Groups. It was an incredible journey! A General Iron‐Catalyzed Decarboxylative Oxygenation of Aliphatic Carboxylic Acids onlinelibrary.wiley.com/doi/10.1002/an…

Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

This might look like a reaction you think is well established, but it’s not been possible before now. Here’s a modular and practical process to make these molecules in a single step. Great work by Alex, Roopender Kumar and Rachel that’s finally online. onlinelibrary.wiley.com/doi/10.1002/an…

Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

A modular dual catalyst system enables tuneable alkene chloro-arylation to highly functionalized chloroalkanes. Congrats to Bo, Ala, Daniel, Katherine and Jean. Out now in Angewandte Chemie onlinelibrary.wiley.com/doi/10.1002/an…

The Gaunt Group (@gaunt_group) 's Twitter Profile Photo

Our Carbonyl Azinylative amination (CAzA) for the synthesis of α-heteroaryl amines is now out in Angewandte Chemie! Congrats Alex (Alex Rafaniello), Roopender (The Kumar Lab) and Rachel!šŸŽ‰ Read it here šŸ‘‡ onlinelibrary.wiley.com/doi/10.1002/an…

Our Carbonyl Azinylative amination (CAzA) for the synthesis of α-heteroaryl amines is now out in <a href="/angew_chem/">Angewandte Chemie</a>! 
Congrats Alex (<a href="/alex_rafaniello/">Alex Rafaniello</a>),  Roopender (<a href="/TheKumarLab1/">The Kumar Lab</a>) and Rachel!šŸŽ‰
 Read it here šŸ‘‡ 
onlinelibrary.wiley.com/doi/10.1002/an…
Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

Here’s a new paper from our amine synthesis program. pubs.rsc.org/en/content/art… Led by Milo Smith and supported by Ryan Kang and Roopender Kumar, this works provides a mild way to make branched 2’-alkylamines Follow Milo Smith as he moves onto his next adventure with Shenvi Lab

Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

Here’s another contribution to our amine synthesis platform. A modular, practical and general carbonyl acylative amination to alpha-amino amides and ketones. Great work by Jianzhong Liu. He’s looking for academic positions and is definitely one to watch. pubs.acs.org/doi/10.1021/ja…

Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

Here’s a straightforward and practical way to make heteroaryl substituted alkyl amines. Surprising how few methods generate this type of useful functionality. Great work by Alex (now at Dr Reddy’s), Roopender Kumar (Assist. Prof at UCL) and Rachel (starting final year of PhD).

Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

New from our photocatalytic multicomponent amine synthesis program. A mechanistically distinct method for the generation of unbiased a-amino radicals formed from iminium reduction. Great work by Harry, who solved some challenging problems in this project. pubs.acs.org/doi/10.1021/ja…

Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

Come and join our team. We have an exciting Synthetic Chemistry PhD opportunity in the The Gaunt Group (starting Oct 2025) in collaboration with AstraZeneca. It will focus development of new catalytic activation modes for the synthesis of novel scaffolds. jobs.cam.ac.uk/job/48481/

Anastasios Polyzos (@polyzosap) 's Twitter Profile Photo

Very excited to share our latest protocol in Nature Catalysis for photocatalytic generation of alkyl carbanions - no need organometallic reagents or reducing metals. Starting from alkene feedstocks, it works with diverse carbon electrophiles. šŸ’„ A Herculean effort led by

Very excited to share our latest protocol in <a href="/NatureCatalysis/">Nature Catalysis</a> for photocatalytic generation of alkyl carbanions - no need organometallic reagents or reducing metals. Starting from alkene feedstocks, it works with diverse carbon electrophiles. šŸ’„

A Herculean effort led by
Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

The The Gaunt Group are looking for two enthusiastic and talented researchers to join our dynamic team in Cambridge, as postdocs. If you are interested in developing cutting edge synthetic chemistry across a wide range of areas relating to catalysis, apply at jobs.cam.ac.uk/job/49113/

The Gaunt Group (@gaunt_group) 's Twitter Profile Photo

Happy to see our Carbonyl Azinylative Amination work by Alex, Roopender and Rachel forming diverse heteroarylaklyamines using in situ generated heteroarylindium species highlighted in ACS Publications OPR&Ds new items of interest! pubs.acs.org/doi/10.1021/ac…

Matthew Gaunt (@matthewgaunt8) 's Twitter Profile Photo

We are excited to share our new work on one carbon alkene homologation. We can iteratively homologate terminal and internal alkenes in simple and complex molecules using this method. Great work by Marcus that opens up lots of exciting opportunities for us. nature.com/articles/s4158…