Come and join us! Lots of cool psatial data and interesting questions to drive our knowledge on duchenne therapies

Extremely grateful for receiving the LSBR Fellowship! In this project we are investigating the drivers of acute myeloid leukemia with myelodysplastic related changes. Erasmus MC @erasmusmcblood #LSBR

Happy to report that we have received the Erasmus MC2 Research Innovation Grant! Sanne Massaar and the team will investigate the driver mechanisms behind disease progression in myeloid neoplasms. #MDS #AML #ErasmusMC #EMC

A fully funded PhD Position available in the Sanders lab focusing on single cell transcriptomics and spatial multiomics in #leukemia! Interested in novel technologies centered on single cell biology! Please apply! werkenbijerasmusmc.nl/en/vacancy/100…

PhD candidate to study the bone marrow microenvironment in leukemia Mathijs Sanders Using cutting-edge technology, you will investigate the cell-intrinsic and cell-extrinsic drivers of AML. jobrxiv.org/job/erasmus-me… #single_cell_biology #spatial_multio... jobrxiv.org/job/erasmus-me…

Proud of the review by Roger Mulet-Lazaro on "Oncogenic Enhancers in Leukemia" in Blood Cancer Discovery in August issue. Great stuff for teaching! aacrjournals.org/bloodcancerdis… RogerMulet Blood Cancer Discovery

Peter Campbell leaves the Sanger Institute at the end of the year to become Quotient's CSO. A mentor and one of my favourite scientists. His foundational, profound and creative contributions to cancer genomics and somatic evolution have truly shaped those fields. [1/7]

Interested in non-coding alterations, large-scale genomics, leukemia? Collaboration between Charles Mullighan and Teachey labs. Genomic analysis of >1300 WGS/WTS/WES samples from T-lineage acute lymphoblastic leukemia, out now in nature nature.com/articles/s4158… Highlights (7):

Join us! The Machado Lab at Cambridge University is looking for an enthusiastic RA to be a core member of the team and lead the lab's data generation efforts, seeking to understand how tumour and immune cells co-evolve and contribute to cancer progression. jobs.cam.ac.uk/job/47922/

🚨 Excited to share our latest paper in Cell identifying how under-replicated chromosomes in micronuclei become shattered by the Fanconi anemia pathway during mitosis. This work was led by UTSW Graduate School of Biomedical Sciences student Justin Engel. 🧵 (1/13): cell.com/cell/fulltext/…

New review by @sjfhermans, Niek van der Maas, Jurjen Versluis and others, detailing how real-world data can be of added value if collected and used appropriately!

Excited to share our latest study in Journal of Clinical Oncology on improving risk stratification for older patients (≥60 yrs) with Acute Myeloid Leukemia (AML)! We developed a novel prognostic model: AML60+. #Leukemia #AML link: ascopubs.org/doi/full/10.12… 🧵1/9

Our single-cell, pan-cancer analysis of open chromatin in human cancers, done in collaboration with TCGA and the Chang and Corces labs (among others including Illumina), is out in Science today. Congrats to Laksshman Sundaram and all authors! science.org/doi/10.1126/sc…

Today, we have Alexander Bick presenting! Don't miss it. 23 September at 16.00 CET Title: "Clonal hematopoiesis: causes, consequences and management" Link: us06web.zoom.us/j/82722159417

07 October 2024 at 16.00 CET Erasmus Hematology Virtual Lecture. We have: Kellie Machlus, Boston Children’s , with "Unraveling roles for megakaryocytes beyond platelet production through novel model systems" Spread the news! us06web.zoom.us/j/82722159417 Kellie Machlus

Applications for #TRTH2026 are now open! Are you an early-career researcher in translational hematology? The EHA-ASH TRTH program provides a unique opportunity to enhance your research skills with guidance from leading international experts. 🔹 Applications open today, March 15!

The stomach is an organ unique in its function, environment and exposures. How does this affect the mutations that normal cells in the stomach acquire? What does this reveal about the origins of stomach cancer? These questions and more in our Nature paper: nature.com/articles/s4158…

longcallD is a new variant caller for genomic long reads. It jointly calls phased small and structural variants. Single binary, one command line for the whole process. Comparable accuracy to mainstream callers. Great work by Yan Gao. github.com/yangao07/longc…

Read the commentary: Putting AML Differentiation States on the BoneMarrowMap, by Jonas Berger and Livius Penter, online now concurrent with #AACR25. doi.org/10.1158/2643-3…

Delighted to share our latest on longitudinal methylation dynamics preceding cancer. Epigenetic signs of AML appear in blood DECADES before Dx. By brilliant Adriana Fonseca ✅Early cancer ✅Methylation drivers ✅Epimutation rates ✅CpG lineage tracing biorxiv.org/content/10.110…