New paper alert! Circulation UTSW Heart The first paper from my independent lab! great collaboration with Chung Lab ambarish. Congratulations to all the authors! ahajournals.org/eprint/PJQDWT8…

TET2 mutant clonal hematopoiesis promotes heart failure with preserved ejection fraction via proinflammatory pathways ambarish, Amanda Tong, Chung Lab, UT Southwestern Medical Center @mattsegar Daniel Daou Wenhuo Hu Naveen Premnath ahajournals.org/doi/full/10.11…

Our preprint describing the Range Extender element, which is required and sufficient for long-range enhancer activation at the Shh locus, is out in nature. nature.com/articles/s4158…

Thrilled to share that I've been awarded Additional Ventures Single Ventricle Research Fund! This means a lot to me at this stage of my career. I'd like to thank my incredible mentor williampu, collaborators, and Pu Lab members at Boston Children's. I'm on the Academic Job Market!

I am beyond honored and humbled to receive the Pathway to Independence Award (K99/R00) from the NIH NHGRI. Deeply grateful to my mentors, Drs. Kaifu Chen and Yu-Hua Tseng, my many collaborators, and my family and friends for their continuous support.

Excited to share our study out in Circulation identifying the ability of PHF7 to activate cellular reprogramming and recover function in the heart following myocardial infarction. Grateful to Eric N. Olson and the great team who made this work possible! ahajournals.org/doi/10.1161/CI…

We discover RUNX1 as a nodal regulator of human cardiac recovery and uncover a druggable epigenetic mechanism in macrophages that orchestrates functional, structural, and molecular features of organ recovery Lavine Lab Michael Alexanian Amgen 🧪🔬🧬 ImmunoFibHF biorxiv.org/content/10.110…

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency | Science | AAAS science.org/content/articl…

🔴20 Atrial Fibrillation Facts Every Physician Needs to Know in 2025⤵️ #OpenAccess 🔹pointofcaremedicine.com/blog-post/20-a… #Cardiology #FOAMed #MedEd #medstudent #paramedic #Cardiology #CardioEd #medtwitter #meded #CardioTwitter #cardiotwiteros #MedX #cardiovascular #MedTwitter

I'm excited to share our new preprint on LagTag, a method that recovers both past and present chromatin states from the same mammalian cells. biorxiv.org/content/10.110…

Proud to share our study on the role of CHD4 in atrial fibrillation, just out in Circulation. We identified a activating role for CHD4 and show that it is essential to maintain atrial rhythm homeostasis.

Now online: Our latest work describing a gene activating role for CHD4 in conjunction with TBX5 in atrial cardiomyocytes, important for atrial rhythm. Thanks to a great team Wei Shi, Yan Sweat Frank Conlon, williampu, and all other co-authors! ahajournals.org/doi/full/10.11…

TBX5 recruits CHD4 to activate atrial genes and preserve rhythm. Disrupting this axis triggers AF in mice—highlighting CHD4 as a key epigenetic regulator in arrhythmia. Mason williampu Yi Wang ahajournals.org/doi/full/10.11…

Fantastic HFpEF review from experts in the field out in JACC: Basic to Translational Science 🫀❤️‍🔥 jacc.org/doi/10.1016/j.…

Kneuer & colleagues found #HFpEF patients show a unique inflammatory & mitochondrial gene signature in immune cells. Learn how anti-inflammatory treatment improved heart function ahajrnls.org/3JSnjLF Christina Mäder SusanneGaul Philipp Lurz Sebastian Rosch Marion Müller

Congratulations to Eric Olson, Ph.D., founding Chair and Professor of Molecular Biology UT Southwestern Medical Center, on being selected to receive the Louisa Gross Horwitz Prize for groundbreaking research into Duchenne muscular dystrophy. bit.ly/46lL9Z8

Our latest paper is in print today Circulation (second one in under a year). Huge thanks to Jinxi Jinxi Wang for leading this exciting and unexpected discovery of Junctophilin-2 in fibroblasts. Circulation AHA Science @IntMedIowa Carver College of Medicine

#ICYMI: CHD4 and TBX5 control aCM gene expression Mason, williampu Yi Wang

First Sweat Lab conference, AHA Scientific Sessions! It’s been a great opportunity to catch up with dear friends, meet new collaborators, and learn about some amazing science!