We are excited to share that our paper (D. Lindenhofer et al.) on SDR-seq, a combined single-cell DNA-RNA sequencing method, has been published in Nature Methods! 🎉  Watch co-author Julia Bauman’s video on how SDR-seq links coding & non-coding variants to gene expression.

A great cover letter can make or break your manuscript submission. As an editor and author, I've seen how a strong cover letter helps editors grasp your paper’s significance. 🧵 [1/9]

Scientist Paul Mischel is championing the importance of odd rings of DNA in tumors—and their promise as targets for cancer therapy. Learn more: scim.ag/3K5WunA News from Science

Why are there intronic reads in your bulk RNA-seq data? You're not alone—it's common, and the reasons are more layered than you think. Let’s break it down. 🧵

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has

Open access link below..check out our new article on all things retrotransposons in the brain!

There’s nothing like Cedar Street in the fall. Yale School of Medicine

Online now: Comparative analysis of rhesus macaque and human placental organoids highlights evolutionary differences in placentation dlvr.it/TNz9H4

Alternative start codon selection shapes mitochondrial function and rare human diseases: Molecular Cell cell.com/molecular-cell…

Find the article here: science.org/doi/10.1126/sc…

Retroelements orchestrate gut tolerance bit.ly/4qZMm0E

Online now: FOXP3 expression depends on cell-type-specific cis-regulatory elements and transcription factor circuitry dlvr.it/TPFWtc

Predominant mutated non-canonical tumor-specific antigens identified by proteogenomics demonstrate immunogenicity and tumor suppression in CRC dlvr.it/TPGsC4

My lab is recruiting postdoc candidates interested in CRISPR synthetic biology and functional genomics approaches to study and engineer tissue injury responses! hsiunglab.org

The Brain Prize 2025 #webinars uncover how the nervous system drives and responds to cancer - from brain tumours to neural circuit remodeling and cancers outside the brain. brainprize.org/winners/cancer… #CancerResearch #Neuroscience #TheBrainPrize

#CancerNeuroscience

Now online! BRAIN-MAGNET: A functional genomics atlas for interpretation of non-coding variants dlvr.it/TPN2Ly

Evidence of network integration and activity-dependent processes in glioma proliferation and outcomes continues to grow. Exciting talks by Drs Harvey-Jumper, Michelle Monje🎗️ 🟦 and Wolfgang Wick 🇪🇺. SNO 2025 Honolulu UC San Diego Neurological Surgery UCSD Neurosciences #Neurosurgery

Neurons help gliomas grow. Discover how in the first #BrainPrize2025 webinar with @Michelle_Monje and Frank Winkler - pioneering insights reshaping brain cancer research. Watch the webinar: youtu.be/k6Pgbq5IZGI?si… #CancerNeuroscience #Webinar

What molecular functions do transposable elements perform in mammalian cells? We reviewed a flurry of recent papers about TEs to look for trends. New TE mechanisms involve pre- and post-transcriptional regulation, virus-like activity, and guided insertion. link.springer.com/article/10.118…