TET1-mediated germline reprogramming & sperm methylome patterning ft. Rexxi Prasasya, Blake Caldwell, Zhengfeng Liu, Songze Wu, Dr. Marisa Bartolomei (@PennCDB), Johanna Fowler, Steven Cincotta, Diana Laird, Kohli Lab (@PennMedicine) & N. Adrian Leu (@PennVet) tinyurl.com/49rferp4

Reminder that most human embryos are mosaic and trophectoderm biopsies should be carefully used. See Eric Rhon, PhD 🏳️‍🌈 paper investigating outcomes of biopsies in a mouse model: 2024 Jan 5;39(1):154-176.Hum Reprod
pubmed.ncbi.nlm.nih.gov/37994669/

Congrats to Rexxi Prasasya on work showing importance of TET1 to germline reprogramming beyond imprinted & meiosis genes--sperm HMRs. Thanks to collabs-Kohli Lab & Diana Laird Iterative oxidation by TET1 is required for reprogramming of imprintin..sciencedirect.com/science/articl…

Thank you Meena Bewtra!!!!❤️❤️

Looking forward to this new challenge and working with outstanding colleagues. Stay tuned for new initiatives!!

Thank you Paula!! ☺️

Thank you!! And a huge thank you especially to my amazing trainees who did this work, inspiring Penn colleagues and fabulous imprinting, epigenetics and repro friends!! UPenn CDB

PA voters- today’s election is really important! Lots of judges on the ballot, including a PA Supreme Court seat. Polls are open until 8pm. Go make your voices heard!

Welcome Neighbor!!

So pleased that the first author on this paper cited as a key publication for today's Nobel Prize was supported by our NIGMS Cell & Molecular T32. 🍾😀 Katalin Kariko The Drew Weissman Lab Penn Medicine

Congratulations Ana Domingo Muelas and Robin Skory, MD, PhD .
Beautiful work. Thanks for invited us to collaborate.! Eric Rhon, PhD 🏳️‍🌈

Congratulations Patrick!!🍾🎇

Hmmmmmm....How does this make a faculty member feel who is on many Raj lab student thesis committees (even as chair)?🤷‍♀️

Really great visit! Welcome to the FIRbee family. Looking forward to reconnecting in the future. #FIR2023

Congratulations Dr. Marisa Egan. Even though you pronounce your first name wrong..🤣 you have been a joy to work with on the CMB TG!

Proud of Penn’s rich history in vaccine development! Stop by the PennMedicine Smilow Lobby to check out the incredible new mural!

Congratulations to Ken Zaret (Zaret Lab) and Susan Weiss (@weisssr) from PSOM on their election to the NAS! Well deserved!! #NASmembers

Many thanks to ⁦Anne Ferguson-Smith⁩ for presenting a GREAT concluding keynote at #GenomicImorinting23 . Fantastic conference. Thanks to ⁦Wellcome Connecting Science Learning and Training⁩ and co-organizers D, Monks, I. Netchine & E. Maher.

Thank you to Azim Surani for presenting one of the keynotes at #GenomicImprinting23 ⁦Wellcome Connecting Science Learning and Training⁩ wonderful seeing imprinting friends!

Yeah Aimee. Watch out Stanford! Here she comes!!! ⁦Aimee Juan⁩ 👏🏼 #match2023