Acting on a piece of folded RNA (Protein Data Bank 6D3P) with my hands in #AugmentedReality using a Meta Quest 3, backed up by OpenMM running an AMBER md forcefield. All web and accessible to you in some months hopefully! By Fabio Cortes and Lucien Krapp :-)

We proudly announce our latest pre-print CryoSamba, a self-supervised deep denoising algorithm for cryoET: it substantially improves contrast and SNR of the tomograms by amplifying coherent signals while reducing high-frequency noise.

"Five questions with Ryan Flynn" Nature Biotechnology Talked a bit about starting the lab and how we think about science nature.com/articles/s4158…

Excited to join the HHMI NEWS community - made possible by talented lab members, current and former, and amazing colleagues at Harvard Med Cell Bio and beyond!

CONGRATULATIONS ! to Harvard Med Cell Bio faculty Susan Shao and Ed Chouchani, who were both named HHMI investigators! So well deserved and we look forward to all of the exciting science to come! hhmi.org/news/hhmi-inve…

Very excited to have contributed some of our structural biology expertise to this Johannes Walter story! Fantastic work by Tycho Mevissen (seriously, hire him!).

Thrilled to share our latest preprint Johannes Walter! We recapitulated transcription-coupled DNA repair in Xenopus egg extract and identified STK19 as a central player in TC-NER that links stalled Pol II to TFIIH. 🐸 🧬 ➡️ bit.ly/4fgl2Fq

Super thrilled to share that l've been awarded the Boehringer Ingelheim Fonds (BIF) PhD Fellowship for my project in Lucas Farnung 's lab at Harvard Medical School I'm excited to join an amazing network of fellow students and great scientists! #BIF #PhD

Fantastic achievement by Sophie! We are lucky to have you as part of our team.

Excited to share the work of Peiyuan Peiyuan Chai in my lab We found cell surface glycoRNAs, RBPs, and heparan sulfates work together to regulate the **signal transduction** properties of growth factors like VEGF-A HSCRB biorxiv.org/content/10.110…

Check out NuA4/TIP60 in Science Magazine . We show how this molecular Swiss army knife integrates histone exchange and acetylation in one complex to maintain genome stability 🧬 Congrats to zhenlin and @mameri_amel who co-first authored this work! 🧵⬇️ twtr.to/157Oh

Happy to share with the world that the main body of my PhD thesis (and my rotation project) on the mechanism for replisome-mediated parental histone inheritance is published in Cell today🥰! cell.com/cell/fulltext/…

It was a great privilege and joy to present my work at the Social DNAing Webinar Series! 🧬 Watch the recording here (available for a few more days): ➡️ wi.st/46T0WgL Also check out the corresponding preprint: ➡️ bit.ly/4fgl2Fq

Congratulations to graduate students Abdallah Mohamed from our group and Peter Wang from the Bartel lab on determining the structure of human AGO2 in the slicing conformation. This was a challenging project with many exciting results. Read our preprint to learn more!