The Effectiveness of Newer Beta-Lactams for the Treatment of Antimicrobial-Resistant Gram-Negative Meningitis bit.ly/3Tep87r

Twice-yearly lenacapavir just won FDA approval for PrEP - closest thing we have to an HIV vaccine. Trials showed ≥99.9% protection But approval doesn’t equal access. The science delivered. Now policy has to. apnews.com/article/hiv-pr…

People are getting upset about this, but the topic is not the core issue. The entire family of JAMA journals is increasingly filled with low-quality observational studies. I suspect that the root cause is poor peer review.

“I haven’t eaten since last night and now they’re canceling my surgery?” Happens all the time. A new meta-analysis finds little evidence that strict NPO rules reduce aspiration risk. It’s time to question the dogma, and start building risk-stratified, patient-friendly

Starchy carbohydrates aren’t bad but most people overeat them b/c when they are combined w/fats they go from “yum” to “YUM!” & when combined w/fats & sugar many people forget themselves like a meth addict who just scored. Food combinations matter for satiety & removing the brake.

In an AI world, it’s easy to avoid effort. That’s why students need teachers more—to push them toward the hard things now that shape who they become later. #Education #AI #TeachingMatters #FutureOfLearning

Taxonomy shift 🚨 Candida auris has been reclassified as Candidozyma auris (C auris ) to reflect its distinct genetic profile from other Candida species. #IDXposts

Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 My personal feeling is that "Taxonomist" should be added to the DSM IV. Im not sure that any available pharmacotherapy could help treat the diagnosis. But I hypothesize that some of the atypical antipsychotics might help. That would be a good RCT to conduct.

We've not been talking about root causes in healthcare...why do a third of our nation's children now have pre-diabetes or diabetes? We've got to talk about school lunch programs, not just putting every 6-year-old on Ozempic.

Want to know why those other countries have lower brand drugs prices than us ? They don't have PBMs. We are the ONLY country that uses PBMs. Insane

📢 New 📜 Overuse of PPIs poses real risks—nutrient deficiencies, infections, kidney disease & more. Our latest review explores when to deprescribe and how stewardship can guide safer prescribing. ⚖️💊 📝 Read here: mdpi.com/2813-0618/4/3/… #Deprescribing #PPI #Stewardship

Last month I explained why aluminum adjuvants are safe: tiny doses, nearly a century of use, cleared by the kidneys like dietary aluminum. Now we have a landmark study of 1.22 million Danish children (births 1997-2018) followed to age 5, with a check to age 8. Result: no

The FDA just sent WHOOP a warning letter about our feature, Blood Pressure Insights. Let me explain why this is a misguided move from the FDA and why it also undermines health and innovation in the United States. 🧵

“We are going to have dietary guidelines that are based on science, not based on medical dogma.” —Dr. Marty Makary

Yes-Millions of women could have enjoyed the health benefits of hormone replacement, but tragically were never offered it because of dogma about risks. Tomorrow, FDA will convene experts to discuss the medical evidence and nuances of HRT for perimenopausal women--join us online!

🚨IDSA has released the first guidelines for the management and treatment of complicated urinary tract infections (cUTIs)! The new guidelines simplify the prior definitions of uncomplicated UTIs and cUTIs, & address treatment for cUTIs. View guidelines: bit.ly/4lUjN1a

The people who dominate the conversation often have the least to say. Being the loudest voice in the room doesn’t gain respect. It crowds out the contributions of those who speak at a lower volume. It’s better to leave people wanting to hear more than wishing they’d heard less.

If you’ve ever had a completely bonkers schedule then finally got a break & got sick after a few days of rest, congratulations: You learned that cortisol enhances immune system function in the short term. Taper(!) from intense to vacation. Keep your mornings active.

I am proud to partner with Dept. of Agriculture and HHS.gov to establish a clear, federally recognized definition of what constitutes an ultra-processed food. This critical work will help shape our efforts to get at the root causes of chronic, diet-related illness and will empower us to create

What's the optimal number of steps of physical activity that is associated with multiple (9) favorable outcomes? The largest, systematic review of 57 studies, 35 cohorts. 7,000 steps is clinically meaningful; some benefit also seen for 4,000 steps cf 2,000 steps The Lancet