We start reviewing applications in three weeks! Penn Vet is an incredibly supportive environment for junior faculty. Come join us!

How do past worm🪱infections impact #COVID19 disease outcomes? Check out our latest pre-print bioRxiv Immunology where we explore this question in a 🐭 model. biorxiv.org/content/10.110… 🙏 to co-first author Bola Oyesola and team leads Alan Sher and Png Loke 🧵below...

Bola Oyesola, Soo Ching Lee and P'ng Loke Png Loke discuss what helminths have taught us about human immunology too, thinking about challenge infection, self-infection, travellers & endemic populations, and the interaction between immunity and microbiome nature.com/articles/s4138…

Read more on the effects of helminths on the human immune response and the microbiome from @lokepng nature.com/articles/s4138…

HFD drives expulsion of Whipworm via the IL-33/ST2 axis - crazy but it's true! 👉👉 sciencedirect.com/science/articl… Delighted to see this from John Worthington, Grencisgroup @MucusMan Stefano Colombo 🇮🇹🇪🇺 Mary J. Tozer 👩🏼‍⚕️ adura faniyi megan 🪱 & others now Mucosal Immunology & happy to have helped

Out Now in Mucosal Immunology Worthington, Grencis and Thornton labs show that a high fat diet allows clearance of a usually chronic T. muris “whipworm” infection

New exciting work from Png Loke lab in collaboration with Khanna Lab and our lab (Keenan Lacey). Single-cell analysis of CX3CR1+ cells reveal a pathogenic role for BIRC5+ myeloid proliferating cells driven by Staphylococcus aureus leukotoxins biorxiv.org/content/10.110…

Another new preprint on @bioRxiv from Bola Oyesola, @PngLoke, Andrea L Graham, me, et al! In this one, we show that interactions between genotype and environment can shape several aspects of mouse immune phenotype in significant ways: biorxiv.org/content/10.110… 1/

Exposure to fungi can help sterile laboratory mice better model specific features of the human immune system, finds new research from Cadwell Lab Andrea L Graham Png Loke. scim.ag/36V

Delighted to share our recent Nature Immunology study led by Yuanyuan Gao, Yan Wang, and Daniel Chauss, showing that transcription factor EGR2 controls tissue- and disease-specific functions in pathogenic Th17 cells in the CNS. Many thanks to our collaborators!!! rdcu.be/dgL4p

Fantastic start to BOP immunology with great talks from Emma and Jude, successful flow cytometry, and sunsets on the beach!

New work in mice indicates that a history of parasitic infection correlates with improved anti-SARS-CoV-2 responses in the lungs because of enduring changes to alveolar macrophages. Kerry Hilligan Png Loke Read more: scim.ag/3H8

Our preprint has become a paper in Science Advances! Very excited that “Social-spatiotemporal association predicts immunological similarity in rewilded mice” w/ Bola Oyesola, Andrea L Graham Png Loke is finally out in the world. science.org/doi/10.1126/sc… Thread below...

New PARASITOLOGY FACULTY position to start or continue your cutting-edge research program at Univ. of Pennsylvania. Terrific colleagues, facilities, mentorship, & a great city. apply.interfolio.com/138577 Please RT. Trends in Parasitology British Society for Parasitology PEERs in Parasitology (PiP) Women In Malaria

I am excited that our paper demonstrating that genetics and environment interact to determine an individual’s immune phenotype is out today in Nature Immunology. Png Loke, Andrea L Graham, Alec Downie. A thread🧵