Scientists have developed a hematopoietic stem cell transplantation protocol that reconstructs a healthy blood system and prevents blood cancers in old mice. This approach has the potential to be used in the prevention of immunosenescence. lifespan.io/news/non-toxic… By Arkadi Mazin

We present the highlights and research updates from the 2025 Longevity Summit Dublin! lifespan.io/news/the-2025-… Aubrey de Grey Michael Ringel, JD PhD Jennifer Garrison Cyclarity Therapeutics NaNotics Life Biosciences

A recent study showed that a psychedelic compound found in hallucinogenic mushrooms has anti-aging properties. It extended lifespan in mice and positively impacted a few hallmarks of aging in human cell lines. lifespan.io/news/a-hallu... By: Anna Drangowska-Way

Researchers created cells that express the regenerative factor GDF11. They ameliorated lung fibrosis in both cellular and mouse models. lifespan.io/news/engineere… By: Josh Conway

Applying AI to reanalyze the data from a failed Alzheimer’s trial revealed that one subgroup of patients showed a robust effect in slowing the disease progression, but the effect was masked by analyzing data for all patients together. lifespan.io/news/ai-reveal… By: Arkadi Mazin

A recent discovery suggests that extracellular vesicles (EVs) derived from antler blastema progenitor cells (ABPCs) restore bone mass to rhesus macaques. lifespan.io/news/vesicles-… By: Josh Conway

A combo of two drugs, already approved by the FDA, effectively rescued Alzheimer’s in mice. People who take these drugs are statistically less likely to get the disease. lifespan.io/news/fda-appro… By: Arkadi Mazin

In a recent study, the researchers have built organ-specific models that revealed the differences in the speed of organ aging and can predict the odds of diseases and mortality risk based on organ-specific proteins found in plasma. lifespan.io/news/organ-spe… By: Anna Drangowska-Way

Study of the cancer-linked gene DNMT3A showed its role in multiple processes, including telomere length and the regulation of uncontrolled stem cell proliferation. Those processes were independent of its role in methylation. lifespan.io/news/a-gene-th… By: Josh Conway

🚶‍♀️🚶You can get most of the health benefits (and there are many) by clocking fewer steps than previously thought! A new meta-analysis suggests that around 7,000 steps a day seems to be the sweet spot for most health benefits of walking. lifespan.io/news/7000-step… By: Arkadi Mazin

Researchers have published the discovery of a protein that inhibits osteoarthritis in mice by diminishing fatty acid production. Targeting this protein is a valid and viable potential therapy for treating osteoarthritis in people. lifespan.io/news/fighting-… By: Josh Conway

In downtown San Francisco, a ‘vertical pop-up village’ called Viva Frontier Tower is becoming a hub for longevity, AI, crypto, and robotics. We are pleased to share the highlights from the first longevity conference hosted there. lifespan.io/news/the-tale-… By: Arkadi Mazin

In a recent study, the antiviral drug maraviroc reduced senescence and improved muscle health in aged mice, suggesting maraviroc's potential as a good candidate for sarcopenia. lifespan.io/news/rejuvenat… By: Anna Drangowska-Way

In a recent study, the researchers report on the connection between Alzheimer's-related protein aggregates, senescent cells, and osteoporosis. They suggest a link between bone loss and amyloid accumulation in bone tissue. lifespan.io/news/senescent… By: Josh Conway

The July Rejuvenation Roundup is here! Catch up on the biggest #longevity news and recent reports of little-known avenues for fighting age-related diseases. Learn more: lifespan.io/news/rejuvenat…

In a new study, the researchers have found that metformin’s activity might be mediated by the brain and identified a specific protein that regulates the effect. These findings open the door for new diabetes and anti-aging therapies. lifespan.io/news/study-fin… By: Arkadi Mazin

Researchers have developed a clock 🕰️ that estimates brain 🧠 age based on gene expression and cellular function changes. They used this clock to identify potential interventions against age-related neurodegeneration. lifespan.io/news/a-brain-c… By: Josh Conway

Using a trimmed, benign form of cholera toxin and a human antibody, scientists have created a chimeric construct that can deliver protein cargo via the intestine. This technology could potentially replace cumbersome injections. lifespan.io/news/study-pav… By: Arkadi Mazin

Smoking tobacco is detrimental to health. However, recent research suggests that nicotine itself can be beneficial. An example is a study that reported that long-term nicotine consumption had a positive impact on motor function in mice. lifespan.io/news/nicotine-… By: Anna Drangowska-Way

🧫 A new study showed that growing older cells in a youthful medium causes them to behave and function more like younger cells, suggesting a new method of creating stem cell-based therapies. lifespan.io/news/a-better-… By: Josh Conway