Our Mitsuhiro Matsuda&Hanako Hayashi's "Human Time vs Mouse Time" project has been published　Science Magazine Human segmentation clock(5h oscillation period) is slower than mouse (2h period) because multiple biochemical reactions are slower in human cells science.sciencemag.org/content/369/65…

Our work #aboutime "Species-specific pace of development is associated with differences in protein stability" is now published science.sciencemag.org/content/369/65…. What determines the pace of embryonic development?

Yes - The amazing observation by Denis Denis Duboule and others (hourglass model), where morphological features are more similar at mid-embryogenesis (roughly) between species, holds true at the level of developmental enhancers. Fun collab with Marc Marc RobinsonRechavi @[email protected] and Jialin Jialin.Liu

A changing waddingtonian landscape in vivo versus in vitro? Conserved developmental trajectories in vitro across species can vary in vivo due to extraembryonic signals or morphological constrains (geometry). Interesting proposal to be tested in space and time

Four years' work, 178 billion sequencing reads, and nearly 5 million cells went into constructing atlases of gene expression and chromatin accessibility in human development, out now.

The Citizen Kane of Cell Division Walther Flemming published this time-lapse of a dividing cell in 1882. He drew the data by hand while looking in his microscope. #CellBiology #microscopy #SciArt

Developing kidney innervation #FluorescenceFriday

Got somites? Beauty rat snake (Elaphe taeniura) embryo. 72 hr after oviposition. Bertola et al. bit.ly/33FHwwg

Thrilled to share our work on timing of cell polarity in mouse development is finally out on Science! Special thank to my Phd supervisor Magdalena Zernicka-Goetz Jake Cornwall-Scoones , Matt Thomson for the great math model, and Peizhe @Charlot80900146 and everyone Zernicka-Goetz Lab! science.sciencemag.org/content/370/65…

So happy to share with you our last paper that deals with Human, Monkey, Rabbit and Mouse inter-species chimeras ! Such a nice way to end 2020 ans start 2021 ! Thanks StemCellReports Martin Pera and the reviewers ! doi.org/10.1016/j.stem…

Herding cells isn't all sheepdogs/roses. Some tissues hate taking orders. Our new work w/ GS Gawoon Shim + Prof. Devenport shows: (1) more communal cells resist bioelectric herding; (2) disrupting cell-cell adhesion improves herding + healing lab skin wounds! biorxiv.org/content/10.110…

Meet Brookesia nana, the Nano-Chameleon, probably the world's smallest amniote vertebrate! We just published its discovery in Scientific Reports: nature.com/articles/s4159… doi.org/10.1038/s41598… Read more about it here: markscherz.com/archives/4800 📸Frank Glaw

A new story from the lab published in Nature today. We found an intriguing cell competitive interaction between primed PSCs among different species! Human (green) are actively eliminated by mouse (red) cells.

Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment science.sciencemag.org/content/371/65…

Bilateral gynandromorphs - half male/half female. Mechanism? @___SDB___ the Node SXD Journal

My sister made this banner for our lab. 🥰

These cellular clocks help explain why elephants are bigger than mice nature.com/articles/d4158…

Stunning movie! What is that beautiful ring of tubulin doing in the ventral region?

In a major scientific advance, a pig kidney is successfully transplanted into a human npr.org/2021/10/20/104… @___SDB___