As some of you might know, I have helped cofound this startup with colleagues Wendy Chung and Francesco Lotti focusing on RNA-based therapeutics. We are up and running at Alexandria LaunchLabs on the Columbia Medical Center campus. Now we are hiring #RNA enthusiasts to join!…

This is how I first learned about biochemistry. RIP Lubert Stryer.

It breaks my heart to see how much international scientists - especially from the “global south” (or east!) - have to sacrifice. We don’t give them nearly enough credit for it!!

This 👇👇 I’ve never understood why international postdocs in US labs are ineligible for nih fellowships - these scientists contribute so much to our research landscape!

First lab retreat of the Steckelberg lab in the Catskills! Had a wonderful time with this amazing team. 2 days of creative science, hiking, games, great food and more - and only 1 person fell into a waterfall.

This is gonna single handedly kill the german academic competence. Without offering resources to provide the said permanent contracts, this ruling will put immense pressure on budding scientists in their formative phases.

Exciting science in the lab of my wonderful new colleague, Ya-Cheng! I cannot think of a better place to train and do science👇👇👇

liao-lab.org Our newest faculty member, the great Ya-Cheng Liao has a lab website! Students and Postdocs the Liao lab is the place to be these days

It was fun to write this short perspective with Sophie Korn on the discovery of protein RNAylation by kathaRiNA Höfer and team. Bacteriophages are a treasure trove of cool biology 😎

Thrilled to share our work on how type V-K CRISPR-associated transposases (CASTs) select their target sites, now published in Science Magazine!
science.org/doi/full/10.11…
In this study, we've enhanced the accuracy of type V-K CASTs up to 99%.🧵 on the bioRxiv version below:…

Check out our latest: Using smFRET, we determine an entirely new mechanism for mRNA activation. As part of this work, we assign novel functions for each of the eIF4F components, including a 'hopping' activity of eIF4G and a 'strippase' activity of eIF4A. 🔬biorxiv.org/content/10.110…

Big update: we're hiring a new lab manager!!

Come join a fantastic group of scientists in the Sternberg Lab at Columbia University, in the heart of New York City, and contribute to cutting-edge CRISPR and genome engineering research. Please re-post and DM me with your interest

Thrilled to share this study! Our lab discovered neurons are special cells with lots of immunostimulatory #dsRNA structures! Huge congrats to cofirst authors Tyler TheScienceAuthority and Heegwon heegwon.shin. Great collaboration with Hynek Wichterle, Yuefeng Huang, Lena Steckelberg.

Happy to see this beautiful paper by
Hachung Chung at Columbia University
and colleagues finally in print: Exceptionally high dsRNA levels through 3' UTRs lengthening protect neurons from viral infection, but also lead to neuroinflammation. science.org/doi/10.1126/sc…

Fascinating mechanistical insight into dsRNA-mediated basal level antiviral immunity in human neurons. Fully amazed if only because of our similar observation on TLR3-dependent basal level IFN-b antiviral immunity in human neurons DOI: 10.1172/JCI134529. science.org/doi/10.1126/sc…

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So well deserved!! Congrats 🎉

A great place to start your independent career with supportive colleagues. Come join us!

Please spread the word: Open PhD position Stephanie Kath-Schorr in the famework of TIDE (RTG 2591) (RTG 2591)! Department of Chemistry (University of Cologne) Universität zu Köln

Burroughs Wellcome Fund And Charles H. Revson Foundation Establish Partnership To Support Minority Scientists bwfund.org/news/pdep_revs… #bwfpdep