 
                                Ashley Laughney
@laughneylab
Associate Professor @weillcornell @wcm_MeyerCancer Systems Biology of Metastasis
ID: 963618321630457858
https://laughneylab.com/ 14-02-2018 03:38:05
509 Tweet
1,1K Followers
949 Following
 
         
        Sincerest of thanks to the Pershing Square Sohn Cancer Research Alliance for supporting scientists, taking risks on new ideas, and to the amazing teams working to realize them! Congrats to all awardees.
 
        With my wonderful Weill Cornell Medicine colleagues #ISMB2024 Hagen Tilgner / @[email protected] Ashley Laughney Ekta Khurana
 
                        
                    
                    
                    
                 
        Our first of a pair of reviews on #Chromosomal_Instability is out in NatureRevClinOncol on targeting CIN in patients with #cancer written with the amazing Duaa Al-Rawi, MD PhD Emanuele Lettera Jun Li Melody Di Bona nature.com/articles/s4157…
 
        Our second of a pair of reviews on how #Chromosomal_instability #CIN drives #cancer progression is out in Nature Reviews Genetics Reviews led by the talented Xuelan @itsalyourpal Jun Li Melody Di Bona nature.com/articles/s4157…
 
        Our new study, published today Cancer Discovery, reveals that iron chelation therapy unleashes innate immune responses that control #OvarianCancer. Congrats to first author Tito Sandoval and the whole team. #Immunotherapy Weill Cornell Medicine Weill Cornell Medicine Ob/Gyn 👇doi.org/10.1158/2159-8…
 
                        
                    
                    
                    
                 
        Very happy to have DNA O-MAP out! The DNA version of this work, started from a simple premise: how can we measure the proteome at any genomic loci in (nearly) any cell? This was a great collaboration with @oligopain, and led by Yuzhen Liu and Chris McGann. 1/8🧵
 
        1/n 🚨 🧬Our paper on the role of #mitochondria and free radicals in promoting the collapse of #Cancer #micronuclei is out in Science Magazine today. A story led by the brilliant Melody Di Bona it started with a simple question: why do micronuclei rupture? science.org/doi/10.1126/sc…
 
                        
                    
                    
                    
                 
        Together with Charles Swanton, delighted to share that our new tool, MHC Hammer - which can detect different types of HLA disruption - mutation, loss, RNA repression and alt. splicing - is now out in #NatureGenetics and available to use…nature.com/articles/s4158…... 🧵below
 
        Tumor Heterogeneity and Evolution: Nicholas Navin, Christina Curtis, and Ashley Laughney will address this topic in an educational session at #SABCS24 (December 10-13). Learn more: bit.ly/4eNLvcq Nicholas Navin Christina Curtis Ashley Laughney
 
                        
                    
                    
                    
                 
        Congratulations to Dr. Victor R. Ambros, former member of the Dartmouth 🌲 Dept. of Biological Sciences and Geisel Dept. of Genetics, for being awarded the 2024 #NobelPrize in Physiology or Medicine, for the discovery of microRNA. home.dartmouth.edu/news/2024/10/f…
 
         
        We hope to see you Thursday for the next WCM Englander Institute for Precision Medicine #PrecisionMedicine Journal Club presented by Tri-I CBM Ethan Earlie on Thursday, April 24th from 3-4 pm in Belfer #1401 and via Zoom (DM for details)!
 
         
        Join us for the next WCM Englander Institute for Precision Medicine #PrecisionMedicine Journal Club where Tri-I Computational Biology and Medicine (Tri-I CBM) graduate student Austin A. Varela (Austin A Varela) will present a nature paper from Sept. 2024!
 
                        
                    
                    
                    
                 
        (1/2) A very exciting milestone for Volastra Therapeutics and the field of #Chromosomal_Instability. Early escalation data for our KIF18A inhibitor, VLS-1488, show excellent safety and promising efficacy in heavily pre-treated ovarian cancer patients. businesswire.com/news/home/2025…
 
         
         
                        