Ashley Laughney (@laughneylab) 's Twitter Profile
Ashley Laughney

@laughneylab

Associate Professor @weillcornell @wcm_MeyerCancer Systems Biology of Metastasis

ID: 963618321630457858

linkhttps://laughneylab.com/ calendar_today14-02-2018 03:38:05

509 Tweet

1,1K Followers

949 Following

Ashley Laughney (@laughneylab) 's Twitter Profile Photo

Sincerest of thanks to the Pershing Square Sohn Cancer Research Alliance for supporting scientists, taking risks on new ideas, and to the amazing teams working to realize them! Congrats to all awardees.

Samuel Bakhoum (@samuel_bakhoum) 's Twitter Profile Photo

Our first of a pair of reviews on #Chromosomal_Instability is out in ⁦NatureRevClinOncol⁩ on targeting CIN in patients with #cancer written with the amazing ⁦Duaa Al-Rawi, MD PhD⁩ ⁦Emanuele Lettera⁩ ⁦Jun Li⁩ ⁦Melody Di Bona⁩ nature.com/articles/s4157…

Samuel Bakhoum (@samuel_bakhoum) 's Twitter Profile Photo

Our second of a pair of reviews on how #Chromosomal_instability #CIN drives #cancer progression is out in ⁦Nature Reviews Genetics⁩ Reviews led by the talented ⁦Xuelan⁩ ⁦@itsalyourpal⁩ ⁦Jun Li⁩ ⁦Melody Di Bona⁩ nature.com/articles/s4157…

Juan Cubillos-Ruiz (@jcubruiz) 's Twitter Profile Photo

Our new study, published today Cancer Discovery, reveals that iron chelation therapy unleashes innate immune responses that control #OvarianCancer. Congrats to first author Tito Sandoval and the whole team. #Immunotherapy Weill Cornell Medicine Weill Cornell Medicine Ob/Gyn 👇doi.org/10.1158/2159-8…

Our new study, published today <a href="/CD_AACR/">Cancer Discovery</a>,  reveals that iron chelation therapy unleashes innate immune responses that control #OvarianCancer. Congrats to first author <a href="/titosandoval84/">Tito Sandoval</a> and the whole team.  #Immunotherapy <a href="/WeillCornell/">Weill Cornell Medicine</a> <a href="/WCM_OBGYN/">Weill Cornell Medicine Ob/Gyn</a> 👇doi.org/10.1158/2159-8…
Devin Schweppe (@dschweppe1) 's Twitter Profile Photo

Very happy to have DNA O-MAP out! The DNA version of this work, started from a simple premise: how can we measure the proteome at any genomic loci in (nearly) any cell? This was a great collaboration with @oligopain, and led by Yuzhen Liu and Chris McGann. 1/8🧵

Samuel Bakhoum (@samuel_bakhoum) 's Twitter Profile Photo

1/n 🚨 🧬Our paper on the role of #mitochondria and free radicals in promoting the collapse of #Cancer #micronuclei is out in Science Magazine today. A story led by the brilliant Melody Di Bona it started with a simple question: why do micronuclei rupture? science.org/doi/10.1126/sc…

1/n 🚨 🧬Our paper on the role of #mitochondria and free radicals in promoting the collapse of #Cancer #micronuclei is out in <a href="/ScienceMagazine/">Science Magazine</a> today. A story led by the brilliant <a href="/melodyDiBona/">Melody Di Bona</a>  it started with a simple question: why do micronuclei rupture?
science.org/doi/10.1126/sc…
Nicholas McGranahan (@nickymcgranahan) 's Twitter Profile Photo

Together with Charles Swanton, delighted to share that our new tool, MHC Hammer - which can detect different types of HLA disruption - mutation, loss, RNA repression and alt. splicing - is now out in #NatureGenetics and available to use…nature.com/articles/s4158…... 🧵below

SABCS (@sabcssanantonio) 's Twitter Profile Photo

Tumor Heterogeneity and Evolution: Nicholas Navin, Christina Curtis, and Ashley Laughney will address this topic in an educational session at #SABCS24 (December 10-13). Learn more: bit.ly/4eNLvcq Nicholas Navin Christina Curtis Ashley Laughney

Tumor Heterogeneity and Evolution:
Nicholas Navin, Christina Curtis, and Ashley Laughney will address this topic in an educational session at #SABCS24 (December 10-13). Learn more:
bit.ly/4eNLvcq
<a href="/nicholas_navin/">Nicholas Navin</a> <a href="/cncurtis/">Christina Curtis</a> <a href="/LaughneyLab/">Ashley Laughney</a>
Geisel School of Medicine at Dartmouth (@geiselmed) 's Twitter Profile Photo

Congratulations to Dr. Victor R. Ambros, former member of the Dartmouth 🌲 Dept. of Biological Sciences and Geisel Dept. of Genetics, for being awarded the 2024 #NobelPrize in Physiology or Medicine, for the discovery of microRNA. home.dartmouth.edu/news/2024/10/f…

Juan Cubillos-Ruiz (@jcubruiz) 's Twitter Profile Photo

Our new study published today nature uncovers that Transgelin 2 preserves T cell lipid metabolism and anti-tumor activity. Transgelin 2 is silenced in dysfunctional TILs, and restoring its expression enhances CAR-T cell therapy in #OvarianCancer 👇nature.com/articles/s4158…

Samuel Bakhoum (@samuel_bakhoum) 's Twitter Profile Photo

Another elegant study by @eileen_parkes group showing how chronic #cGAS #STING activation from #Chromosomal_instability shapes the tumor microenvironment of esophageal #cancer biorxiv.org/content/10.110…

Samuel Bakhoum (@samuel_bakhoum) 's Twitter Profile Photo

(1/2) A very exciting milestone for ⁦Volastra Therapeutics⁩ and the field of #Chromosomal_Instability. Early escalation data for our KIF18A inhibitor, VLS-1488, show excellent safety and promising efficacy in heavily pre-treated ovarian cancer patients. businesswire.com/news/home/2025…

MD Anderson Cancer Center (@mdandersonnews) 's Twitter Profile Photo

Early findings from a first-in-human trial of VLS-1488, an oral KIF18A inhibitor, show promising anti-tumor activity in heavily treated ovarian cancer. No dose-limiting toxicities were observed. Presented by Dr. Ecaterina Dumbrava at #ASCO25. #EndCancer

Early findings from a first-in-human trial of VLS-1488, an oral KIF18A inhibitor, show promising anti-tumor activity in heavily treated ovarian cancer. No dose-limiting toxicities were observed. Presented by Dr. Ecaterina Dumbrava at #ASCO25. #EndCancer