🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Congrats to outstanding UCSD undergrad intern Mason, mentored by the exceptional Alex Alexandra Salazar. Please come back for your PhD at the Scripps Research Graduate Program, Mason!

Jie has an amazing knack of identifying incredibly cool biological systems that give rise to unexpected, impactful findings! Anyone lucky enough to join his group at UVA will receive outstanding mentorship while pursuing inspiring, top-tier research! Please Retweet

We were incredibly disappointed with the lack of code or executable accompanying the publication of AF3 in nature . This contradicts scientific principles of the ability to evaluate, use, and build upon existing work. zenodo.org/records/111798…

There is no such thing as AlphaFold3. There is only alphafoldserver.com. The difference is throttling rigorous scientific and biomedical research.

Hey all new(ish) structural biology PIs out there - I started a slack workspace geared toward us! If you’d like to join, DM me your email and method(s) of choice, and I’ll add you to the group.

We always thought nucleotide state strictly defined AAA+ conformation, but Jeff Mindrebo's work on mito LONP1 suggests more is at play - substrate interactions also drive protein translocation! Revisiting & rethinking the hand-over-hand mechanism: tinyurl.com/49y7a6h6

The registration deadline of the meeting "Emerging theoretical approaches to complement single-particle cryo-electron microscopy" is today! Join us in Trieste, Italy, with an outstanding list of speakers. biophysics.org/2024trieste#/ Pls RT & Apply !

Some thoughts on the current state of single particle cryo-EM map/model validation. (TLDR: preferred orientation remains a big problem, ❤️ Q-scores. There's been progress, but there's still more to do. ) authors.elsevier.com/sd/article/S09…

Apply now and come work at Vanderbilt University with me and my outstanding colleagues in the Center for Structural Biology! Would be thrilled to recruit more #NMR friendly colleagues! 😉🙌 Vanderbilt Center for Structural Biology Vanderbilt Biochemistry Vanderbilt School of Medicine Basic Sciences

Mesoscale Explorer molstar.org/me/ Paper out !! Excellent work with @asrmoin David S. Goodsell 🏳️‍🌈  and David Sehnal doi.org/10.1002/pro.51…

Ready for the final day of the BPS meeting on 'Emerging Theoretical Approaches to Complement Single-Particle Cryo-EM' in Trieste! 🔬 We had outstanding speakers, great science, and friendly atmosphere. Thanks to Biophysical Society CECAM, Giulia Palermo Rommie Amaro Lander Lab!

Proof our lab skills are cutting-edge—both at the microscope and the (pumpkin carving) bench! 🎃🔬 #CryoEM #PumpkinScience Scripps Research

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The human mitochondrial ClpXP is uniquely assembled and regulated compared to its bacterial counterparts. Congrats to Kelly Chen on her years of hard work on this challenging complex! biorxiv.org/content/10.110…

You can now follow us at bsky.app/profile/lander…

Proud of new work tinyurl.com/yhz4c6ry from the lab by Zhicheng (Chen) Cui Zhicheng Cui | 崔志成 using single-particle cryo-EM on liposomes to show how mTORC1 integrates nutrient and growth factor signaling at lysosomes, collab. w/ Gennaro Napolitano, A. Esposito, and A. Ballabio.

Congrats to our grad students who pitched therapeutic targets at this year's Scripps Research Graduate Program Drug Discovery Shark Tank - particularly Shelby Shelby Ferrier and Morgan Morgan Gee on their winning proposal to target Cholera toxin subunit B, which raised $4 million!

Last chance to apply to the Cold Spring Harbor #cryoem course this March (application deadline is Jan 15th)! Learn all about sample prep, microscope operation, and image processing at this fun 2-week course kollman lab Jennifer Cash CSHL Courses meetings.cshl.edu/courses.aspx?c…