New paper out! #Aptamer-based proximity labeling guides covalent #RNA modification. #Biochemistry pubs.rsc.org/en/content/art…

Excited to share our work on a-TCO’s— a new family of trans-cyclooctenes with high reactivity and improved physiochemical properties that can be accessed as single diastereomers. Congratulations to Jess Pigga for leading this work. doi.org/10.1002/anie.2…

Our Chemical Biology department is offering two #PhD fellowships as part of the #CONSENSE training network. The objectives for the PhD students in the group of Kai Johnsson will be the engineering of new biosensors and biomolecular nanoswitches. Apply now! mr.mpg.de/14507080/job_f…

My first tweet ever to guide you to our new pre-print about a side-by-side kinetic and structural characterization of HaloTag7, SNAP-tag and CLIP-tag. Now available on biorxiv!! biorxiv.org/content/10.110…

In our new preprint, we describe a general strategy to transform rhodamines into highly fluorogenic and blinking probes optimized for different imaging applications and labeling systems. biorxiv.org/content/10.110…

Excited to share recent J. Am. Chem. Soc. using far-red silarhodamines to catalyze activation of rapid bioorthogonal chemistry in vivo. Awesome collaborators Zibo Li, Xinqiao Jia, Luke Lavis, & Colin Thorpe. Great dyes make great photocatalysts! @rhodamine110. pubs.acs.org/doi/10.1021/ja…

Enzyme units stacked on top of each other like a spinal column – look fabulous and contains some very fascinating research! Out now Nature Microbiology nature.com/articles/s4156… mpi-bremen.de/en/Enzyme-skys… Max Planck Institute for Medical Research @BarendsThomas @MicroPhys Max Planck Society #NXR #nitrate #anammox

We are glad that our fruitful collaboration with Georg Fantner lead to the advancements in correlative super-resolution and scanning ion-conductance microscopy imaging. We thank all collaborators! WombacherLab @KYserentant @PhilWerther for fantastic self-blinking dyes

I highly recommend HDyes for live-cell imaging!👍 I was very lucky to have the chance to test these new dyes, and they really outperform, with their high SNR for wash-free labeling. Congrats for the nice work!👏

Richard Wombacher and colleagues (WombacherLab) report a new chemical inducer of proximity based on ABA receptor dimerization by the agrochemical manipropamid. Open access: nature.com/articles/s4158…

Natural product conference #Irsee22 about to start! Great line-up of speakers & topics in the opening session: a talented producer of new natural products, total synthesis of anti-infective drugs & a super-efficient inducer of proximity DECHEMA e.V. WombacherLab Christian Jogler

Happy to share our pre-print about exchangeable HaloTag Ligands (xHTLs): We describe the design and characterization of fluorescent xHTLs expanding the HaloTag repertoire and finding application in 3 super-resolution microscopy techniques! (1/9) biorxiv.org/content/10.110…

A new paper from Kai Johnsson’s group developed a biosensor for visualizing cytosolic and mitochondrial CoA in living cells. Open access: nature.com/articles/s4158…

Hot off the press: @HertenDirk and WombacherLab jointly developed a single molecule fluorescence screening assay for characterizing fluorogenic click reactions to improve bioorthogonal labelling. Credits go to Felix Hild, @PhilWerther and @KYserentant. sciencedirect.com/science/articl…

Do you want to change the color of your biosensor on demand? Still have a large dynamic range? Check our preprint on ChemoX! More about it in the thread! (1/7) Congratulation to the team, in particular the twitterless Lars Hellweg. biorxiv.org/content/10.110…

The MtL Lecture Series continues! 🎉 Join us on 17 May at 3 pm for an insight into the research of MtL Fellow Petra Schwille from Max Planck Institute of Biochemistry (MPIB). Register now 👉 bit.ly/3W1z4BB

What a nice way to finish the week! 🎉Our latest paper is now available online in Nature Chemical Biology. 📚🔬If you missed the pre-print and like biosensors, explore our innovative approach for designing and developing chemogenetic sensors. 💡Check it out here: nature.com/articles/s4158….

We continue with Richard WOMBACHER for the first oral communication ! #ChemBio2024 @reseauSCF