
Sakai Disc Lab
@labsakai
Dai Sakai's research team specialized in #regenmed therapies for IVD repair and deformity corrections. Maintained by @iDeJordy
ID: 1405093870740799497
http://sekitsui.med.u-tokai.ac.jp 16-06-2021 09:28:42
543 Tweet
272 Followers
146 Following



New @JORSpine review examines discogenic #backpain and explores how biomolecular therapies could target pain pathways beyond IVD degeneration showing the need for therapies addressing chronic LBP. Learn more: doi.org/10.1002/jsp2.1… ORS Spine Section #SpineHealth #BioMolecular


New @JORSpine: A new U-Net model automates 3D disc segmentation from spine MRIs, matching manual accuracy and streamlining analysis across diverse ages and degeneration levels. #AI #MRI #MedicalImaging ORS Spine Section doi.org/10.1002/jsp2.7…





📝 New study in Journal of Orthopaedic Research - Spine® underlines link IDD and Tnf-α/Tnfr signaling pathway. Tnfr1/2 #knockout mice showed #TNFR deficiency alleviates age-related and spine instability-induced IDD by enhancing ECM metabolism. See: doi.org/10.1002/jsp2.7… ORS Spine Section ORS Preclinical Models Section



New Journal of Orthopaedic Research - Spine® study identifies IVDD #biomarkers. 🔬 Using advanced #bioinformatics, researchers found 10 hub genes, with #JUNB, #SOCS3, and #CEBPB emerging as top candidates. New diagnosis and therapeutic targets? 🧠💡 🔗 Read more: doi.org/10.1002/jsp2.7… ORS Spine Section


New @JORSpine work on "Spine Tester TO GO"! This innovative tool enables both biomechanical & biological tests on the same specimen, reducing the need for animals & supporting the 3R principle. 🐭🐷🐶 Find work here: 🔗doi.org/10.1002/jsp2.7… ORS Spine Section ORS Preclinical Models Section

New study in @JORSpine exploring #HybridSurgery combining cervical disc #arthroplasty and ACDF offered biomechanical benefits in revision surgery, especially with D-C-D models. Great insights for hybrid surgical strategies! ORS Spine Section Read it here: doi.org/10.1002/jsp2.7…

Calling all ORS Spine Section Members! 🤝 To our friends ORS Spine Section: We’d love to see you at #ISSLS2025 in Atlanta! 🔹 Collaborate with the global spine community 🔹 Present your groundbreaking work 🔹 Propose exciting joint symposia Let’s strengthen our partnership!

