🧬 LESAI Clinical Pearl: Cuidado con el DAS28: No siempre es lo que parece Mira, cuando hablamos del DAS28, no siempre refleja toda la historia. Fíjate que a veces, aunque el número sea bajo, aún puedes sentir dolor o... 🎬 Watch + transcript: rheumascore.xyz/blog/vide...

The SLICC/ACR Damage Index (SDI) measures irreversible organ damage in SLE. SDI ≥1 at year 1 independently predicts 10-yr mortality; each +1 point → 34-46% ↑ death risk. Annual assessment is essential. rheumascore.xyz/blog/sdi/ #Rheumatology #Lupus #SLE #ClinicalScore

Immediate Treatment for Myocardial Infarction Mnemonic: “OBESSE MAN” O – Oxygen B – Beta Blockers E – Enoxaparin (anticoagulation) S – Statins E – Evaluate / Early reperfusion M – Morphine (pain control if needed) A – Aspirin ± ACE inhibitors N – Nitroglycerin Critical Step

Rheumatoid Arthritis management isn’t just about hitting lab targets; it’s about the patient experience. The CORRONA registry showed that despite achieving clinical remission, over 40% of patients still report moderate to severe pain. We’re not just treating numbers; we’re

🧬 LESAI Clinical Pearl: Riesgo Cardiovascular en la Artritis Reumatoide Mira, fíjate que tener artritis reumatoide no solo afecta tus articulaciones. También puede aumentar el riesgo de problemas del corazón. Sé que esto... 🎬 Watch + transcript: rheumascore.xyz/blog/...

The IL-6 inhibitor tocilizumab has shown promise in systemic sclerosis, particularly in lung function preservation. However, the recent study by Khanna et al. (Annals of Internal Medicine, 2023) highlights a potential selection bias with participant eligibility. We can't just

Psoriatic arthritis often plays hide and seek, and missed diagnoses are the norm. The importance of screening for HLA-B27 positivity can’t be overstated—especially since 80-90% of patients with axial spondyloarthritis are positive. It's crucial to integrate clinical findings with

Recent data from the CREDEN-Z study shows that IL-23 inhibitors like guselkumab are proving effective in PsA with an ACR20 response rate of 75% at 24 weeks. Yet, many still default to older TNF inhibitors. The evidence is clear: we need to challenge our biases and embrace newer

Despite declines in illnesses, outpatient visits, and hospitalizations from 2022 to 2024, COVID-19 continues to have a large impact in the US, especially among adults 65 years and older. ja.ma/4aJvghv

🧬 LESAI Clinical Pearl: Toxicidad Retiniana por Hidroxicloroquina: Guía de Detección Hola, ¿cómo estás? Mira, sé que esto de la hidroxicloroquina puede generar preguntas. Fíjate que es importante hacerse un examen de los ojos cada año... 🎬 Watch + transcript:

A surprising number of clinicians overlook the significance of anti-MDA5 antibodies in inflammatory myopathies. Studies show they correlate with a more severe disease course and poorer prognosis. Yet, many still stick to the old-school markers. We need to do better at recognizing

The WOMAC (Western Ontario & McMaster Universities OA Index) is the gold standard PRO for knee & hip osteoarthritis. 24 items across pain, stiffness & physical function. MCID: 9.1 pts total. rheumascore.xyz/blog/womac/ #Rheumatology #Osteoarthritis #ClinicalScore

Long-term glucocorticoid use in autoimmune diseases? The evidence is clear: risks of osteoporosis and fractures skyrocket. The latest data from a meta-analysis (Davis et al., *Annals of Rheumatic Diseases*, PMID: 33589212) showed a 50% increase in fracture risk after just 3

In the phase 3 TETON-2 trial involving patients with idiopathic pulmonary fibrosis, inhaled treprostinil was associated with a smaller decline in forced vital capacity and a lower risk of clinical worsening than placebo over 52 weeks. Full trial results: nejm.org/doi/full/10.10…

RECITE: In a phase 3 trial in patients with persistent chemotherapy-induced thrombocytopenia, 84% of those receiving romiplostim had no chemotherapy dose modifications, as compared with 36% of those receiving placebo (odds ratio, 10.16). Full trial results:

Autoimmune diseases are not a monolith; the intersectionality of genetics, environment, and individual physiology is what makes each case unique. For instance, in Sjögren's syndrome, the presence of anti-Ro/SSA antibodies significantly correlates with systemic involvement and

🧬 LESAI Clinical Pearl: HAQ-DI: Evaluando la discapacidad funcional en artritis reumatoide Mira, ¿has oído hablar del HAQ-DI? Es una herramienta que nos ayuda a entender cómo la artritis reumatoide afecta tus actividades diarias. Fíjate que... 🎬 Watch + transcript:

In the latest ACR guidelines, the push for early imaging in inflammatory arthritis is crucial. Yet, many still cling to the old "watch and wait" model. Crazy, right? We know that initiating therapy early leads to better long-term outcomes. It's time to ditch the inertia and start