Frustrated Kuramoto model on simplicial complex: mathematical framework, generalised order parameter and complex dynamics: endless fun in sight. Thank you Alexis Arnaudon, Robert Peach and Giovanni Petri for seeing it through! arxiv.org/abs/2111.11073

Metronomes on a rolling platform will naturally synchronize. Wait for it. The math is described by the Kuramoto model, also used to describe synchronization in populations of neurons. Video source: wesphysdemo, wikipedia en.wikipedia.org/wiki/Kuramoto_…

A long-waited paper coming from our long term collaboration with Bechir Jarraya's lab. This time we used DBS to induce anesthesia awakening. We measured the impact in behavior, static/dynamic fMRI FC, and EEG. A proper thread next monday! science.org/doi/10.1126/sc…

The bad news is not everyone will agree with your opinions or decisions. The good news is it doesn't matter.

Ketamine gets a lot of attention, but I don't think we put enough emphasis on how crazy it is that a single molecule can take you from rich dissociative hallucinations to complete anesthetic oblivion, with dynamics comparable to both classical psychedelics & GABAergic anesthesia.

"Altered dynamical integration/segregation balance during anesthesia-induced loss of consciousness" 🧠 in collaboration with: Paul Expert timoteo carletti Henrique Fernandes and Prof. Federico Turkheimer supported by Iméra 🇫🇷 biorxiv.org/content/10.110…

New preprint out: "Altered dynamical integration/segregation balance during anesthesia-induced loss of consciousness" biorxiv.org/content/10.110… With the legendary: L.D. Lord timoteo carletti Henrique Fernandes and Federico Turkheimer and support from Iméra

The ultimate test of your knowledge is your ability to convey it to another.

Brain rhythms have been detected for a century, but their generative mechanisms remain under debate. Here's our hypothesis and how we tested it (1/6) nature.com/articles/s4200… Francesca Jakub Vohryzek Prof. Vladimir Litvak find me @vlitvak.bsky.social Renaud Lambiotte Christian Bick, Friston, Kringelbach & Deco

Big paper day! Our first data showing that fMRI can be used diagnostically and prognostically in acutely unresponsive patients in the ICU. Loretta Norton Karnig Kazazian @jpeelle Derek Debicki Davinia Fernández-Espejo and others (not on twitter). onlinelibrary.wiley.com/doi/10.1002/an…

How to do a principled stimulation paradigm? We argue for "Dynamic Sensitivity Analysis" where in-silico whole-brain perturbations are leveraged in guiding experiments. sciencedirect.com/science/articl… Joana Cabral Francesca Yonatan Sanz Perl L.D. Lord Henrique Fernandes Prof. Vladimir Litvak find me @vlitvak.bsky.social

What is the best test to detect consciousness in the ICU? Behavioral exam? fMRI? EEG? Or is it TMS-EEG? We discuss the potential for TMS-EEG measurements of brain complexity to improve care for patients with severe brain injuries in the ICU. link.springer.com/article/10.100… Curing Coma

New preprint! This is the last chapter for my PhD dissertation to see the light of day: I wrote it to be an accessible introduction to information theory explicitly written for the aspiring complex systems scientist. 1/n arxiv.org/abs/2304.12482

New paper out investigating the effect of anesthesia-induced loss of consciousness on the integration/segregation balance (tinyurl.com/5bsy28vd) lead by the fantastic L.D. Lord, with timoteo carletti, Henrique Fernandes and Federico Turkheimer, supported by Iméra

Psychedelics have started to show promise for treatment of depression. We wanted to understand what causal mechanisms are relevant in driving this success. Our latest brain comms paper attempts to shed light on it. academic.oup.com/braincomms/adv…

Prognostication in the ICU is an uncertain art and science. With David Fischer, MD, we review the state-of-the-science in our field and where we are heading in JAMA Neurology: jamanetwork.com/journals/jaman… MGH Neurocritical Care MassGeneralNeuroscience MGH Center for Neurotechnology and Neurorecovery University of Pennsylvania Neurology Curing Coma

Latest one out! Ultrafast, lossless analysis methods for high-dimensional time-series - application to neuroimaging. First for Giuseppe de Alteriis, congrats for seeing it over the line :-) and with Fran Hancock 🇮🇪 🇵🇭 🇨🇭, Eilidh MacNicol, BRAIN, Federico Turkheimer

'Unravelling consciousness and brain function through the lens of time, space, and information' by Andrea Luppi Andrea Luppi, Fernando Rosas 🦋, Pedro Mediano, Athena Demertzi @ADemertzi, David Menon David Menon & Emmanuel Stamatakis Emmanuel A Stamatakis cell.com/trends/neurosc…

The brain is metabolically hungry but most accounts of cognition do not consider the energy cost of neural activity Here we review the metabolic budget of neural homeostasis + cognition; associated evolutionary constraints; plus disturbances in disease osf.io/preprints/osf/…

Covert Consciousness in the ICU A review in collaboration with David Menon Thank you Critical Care Medicine for highlighting this topic, now even more relevant after yesterday's NEJM paper (nejm.org/doi/full/10.10…) journals.lww.com/ccmjournal/abs… MGH Neurocritical Care MassGeneralNeuroscience MGH Neurology