A fitness trade-off explains the early fate of yeast aneuploids with chromosome gains biorxiv.org/cgi/content/sh… #bioRxiv

Almost 80 years ago, Luria and Delbrück measured mutation rate in bacteria. Today, in collaboration with IFOM Lagomarsino we adapted their assay to measure mutation rates before and under treatment in cancer cells. Find out more on Nature Genetics nature.com/articles/s4158…

Yes! Our work quantifying the #evolutionary dynamics and #mutationrate of #colorectal #cancer #persisters is out on Nature Genetics. Proud to be part of this outstanding interdisciplinary teamwork mariangela russo Simone Alberto Sogari Bardelli Lab. You don't want to miss this!

Our web site is on line! spcg.unimi.it

A teaser of Marco's book is out mcltone.github.io/boe/ [check it out before twitter shuts down :/ ] #boe

New Statistical Physics of Cells and Genomes preprint: Metacommunity structure preserves genome diversity in the presence of gene-specific selective sweeps. With Simone Jacopo Grilli Joshua Weitz bioRxiv doi.org/10.1101/2023.0…