Ever wondered how UniDec actually works? Check out Part 5 in the UniDec Tutorial Series: How UniDec Works and Quick Controls youtu.be/j7b8yU1Sn44 Native MS-Guided Structural Biology Center Am Soc for Mass Spec

Excited to have this published in ACS Analytical Chemistry Journals! Great work Marius Kostelic, Ciara, and Hiruni! If you are interested in making mixed lipid nanodiscs, this paper has good recommendations: Assembly of Model Membrane Nanodiscs for Native Mass Spectrometry pubs.acs.org/doi/10.1021/ac…

Mixed-lipid nanodiscs assembled by Michael Marty and team more accurately reflect lipid compositions of mammalian cells, bacteria, and mitochondria. Native mass spectrometry was used to study how these lipid compositions affect peptide incorporation. pubs.acs.org/doi/10.1021/ac…

Congrats to Marius Kostelic on his paper winning the Ron Hites Award!

Excited to share our new preprint on oligomerization of the M2 channel! Really interested to see what people think. Influenza A M2 Channel Oligomerization is Sensitive to its Chemical Environment biorxiv.org/content/10.110…

Promoted to Associate Professor with Tenure! Time to crack open the bottle of Scotch that Weston Struwe gave me when I left Oxford. Thanks to everyone for all your support over the years!

We are excited about the global interest in Computational Tools for Native MS! Looking forward to a great workshop! #nMSTools u.osu.edu/nativems

For those who missed the Native MS-Guided Structural Biology Center Workshop last week, we just released UniDec 5, which includes an new module for CD-MS. Take a look at this tutorial from Marius Kostelic Part 6: UniDecCD (UCD) Deconvolution of Charge Detection-Mass Spectromet... youtu.be/qho7YM6sHhs

Excited to share the preprint for UniDecCD! Anyone curious about CD-MS should check it out. The software is open source, free, and downloadable here: github.com/michaelmarty/U… UniDecCD: Deconvolution of Charge Detection-Mass Spectrometry Data | ChemRxiv doi.org/10.33774/chemr…

New preprint from our lab on AMP-membrane interactions! Interesting story on how lipid tails influence LL-37 oligomerization: Lipid Tails Modulate Antimicrobial Peptide Membrane Incorporation and Activity biorxiv.org/content/10.110…

Really excited about this work by @KeenerEJames looking at how membrane proteins remodel their surround lipid environment in nanodiscs! Also a little sad that this is the last chapter in his thesis. biorxiv.org/content/10.110…

Congrats to Marius Kostelic and collaborators on our latest ACS Analytical Chemistry Journals paper describing UniDecCD, the first deconvolution algorithm for CD-MS data. Some really cool results on natural lipid nanodiscs and AAV particles! The software is free to download. pubs.acs.org/articlesonrequ…

CD-MS resolution of heterogeneous complexes like AAV capsids and natural lipid nanodiscs was greatly improved by deconvolving with UniDecCD, developed by Michael Marty and coworkers. pubs.acs.org/doi/10.1021/ac…

Congrats to our collaborators in the Chen and Wang labs and to Julia Townsend for more great native MS on Mpro! Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity pubs.acs.org/doi/10.1021/ja…

Congrats to Deseree Reid for her excellent paper on FPOP of AMPs in nanodiscs! First FPOP paper from our lab, and some CDMS too! J. of the American Society for Mass Spectrometry Investigating Antimicrobial Peptide–Membrane Interactions Using FPOP in Nanodiscs pubs.acs.org/doi/10.1021/ja…

Really excited to have this preprint out! Using PEG coated nESI tips significantly improves sensitivity for native MS. Check it out! Congrats to Marius Kostelic @ErinBakerNCSU Jack Ryan Craig Aspinwall and Jason! doi.org/10.26434/chemr…

Congrats to Marius Kostelic and Jason for their new paper in J. of the American Society for Mass Spectrometry! They discovered that PEG coating improve sensitivity of native MS, especially of AAV capsids. Awesome work from the team @ErinBakerNCSU Craig Aspinwall Jack Ryan @henrymsandersg1! pubs.acs.org/doi/full/10.10…

Latest paper in the Marty Lab in ACS Analytical Chemistry Journals! We used online temperature ramps with CD-MS to characterize AAV capsid release and dissociation. Great work Marius Kostelic and coauthors! pubs.acs.org/doi/10.1021/ac…

New preprint led by @henrymsandersg1 in collaboration with the Zanni Lab looking at IAPP oligomerization in nanodiscs by native MS doi.org/10.26434/chemr…

Last preprint from Marius Kostelic from our group. An awesome collaboration with Jack Ryan and Baker Lab UNC on combining CD-MS and LC-MS to characterize AAV capsids! Also our first paper with Chrom & Mass Spec DMT mode on our UHMR, which looked great! biorxiv.org/content/10.110…