🧫 Curvotaxis - this phenomenon describes the preferred migration pattern of cells. Did you know that biological cells follow universal physical principals when moving inside our body? #CellBiology #Physics Eberhard Bodenschatz Weizmann Institute
ds.mpg.de/4051469/240318…

Qiang et al revealed cancer cells excrete protons into a polarized extracellular region, driving the pH below 5.3 Nature Biomedical Engineering. The severe acidity is toxic to T cells but not cancer cells, highlighting a tumor survival strategy against immune surveillance.

rdcu.be/dAgFR

Remember, you can vote in #STATMadness once a day! Check out Wyss entries in matchups 7, 9, and 27 with work from the labs of Natalie Artzi, Samir Mitragotri, and george church.
statnews.com/feature/stat-m…

.U.S. FDA approves breakthrough tumor-infiltrating lymphocyte (TIL) therapy for metastatic melanoma #NBTNewsBeat endeavor.moffitt.org/archive/new-br…

Immunity as biophysics at the surface of a T cell dlvr.it/T2tV66

Very excited to see this out in nature where we show the in vivo relevance of liver viscoelasticity in liver cancer! Thank you Natalie J. Torok for having us as part of this study, and huge congrats to first author Weiguo (Jerome), not on twitter. Congratulations to the whole team!

Excited to share our collaborative study led by Natalie J. Torok, out in Nature today! It describes how enhanced matrix viscoelasticity promotes liver cancer progression in the pre-cirrhotic liver.
nature.com/articles/s4158…

Fantastic investigation of macrophages in primary and metastatic #breastcancer by the IdoAmitLab. Bravo to the authors! Differences of macrophages in primary metastatic sites! Are different therapeutic strategies needed? Dan Michaud, PhD & I wrote a commentary describing this work.

💥 Pub.alert : check out our latest review article with Li Tang published Nature Nano today 🤩
📖 We discuss the implications
of biomechanically regulated
#immunosurveillance in #cancer and
other diseases
rdcu.be/dxdQ2
🧵 (1/n)

Harvard SEAS #topicsbioeng is still powering through!!! Yale Michaels CancerCare Manitoba Research University of Manitoba, Harvard University alumni will be kicking it off with an amazing talk on rational immune cell differentiation from pluripotent stem cells using computational and synthetic biology approaches💖

I’m glad we pulled it off. It was great connecting and seeing you all. I hope we stay in touch. And thanks for the brunch recommendation Dr. Carleara Weiss.😀

Transport properties of cells are as important as their biological properties in determining the efficacy of cell therapies. Check out this study from our lab in collaboration with Jennifer Guerriero, PhD led by Kolade Adebowale, Ph.D.

Thank you, Wyss Institute, for covering our work, which was motivated by our desire to understand and quantitatively describe the transport of cell therapies in complex tissue-like environments, using macrophages as an example. Jennifer Guerriero, PhD Samir Mitragotri
wyss.harvard.edu/news/shape-shi…

It was great meeting mentors and friends at #@ABRCMS. Thanks to @nigms, and Irene Hulede + ASM for making this happen #MOSAIC #ABRCMS2023 .

Please join us tomorrow, Friday, 11/17, for a lineup of exciting talks! I am honored to be part of this cohort and excited to share some of our work 😀. Webinar format - happy to answer scientific questions offline. Registration link: czbiohub.zoom.us/webinar/regist…

I am excited to be selected as a speaker at the 2023 Stanford.Berkeley.UCSF Next Generation Faculty Symposium. I am grateful for the opportunity to share some of my work, and I look forward to learning from all the speakers (virtual, Friday, Nov. 17th). berkeleystanfordnextgensymposium.com/2023-featured-…

Excited to be at #AIChE2023 ! I will be at poster 285 at the meet the faculty candidate session (1-3 pm Nov. 5). Talk #1, Nov. 5 @ 5 pm (macrophage tumor infiltration). Talk #2, Nov. 7 @ 9:20 am (monocyte 3D migration in viscoelastic gels.)

Extra seminar treat this week from Professor Daniel Fletcher on 'Mind the gap: Mechanics and signaling at cell-cell contacts!' I am pretty excited about this talk. Harvard SEAS #TopicsBioEng

Thank you so much for organizing Joanna Y. Lee, Ph.D. 🙏! It was a delightful dinner. Looking forward to hearing more about your 3D TME models. And it was pretty exciting to meet my academic grandfather. 😎