🚨 Wow! #ASCO25 ASCO was absolutely massive! 10 NEJM papers published simultaneously 👉 all practice-changing studies ! 🔬✨🧵 See below for these studies 👇@oncoalert

Julian Chavarriaga Rob Hamilton Lucia Nappi Ciara Conduit Alexandros Papachristofilou 👏🏻👏🏻👏🏻👏🏻 excelente trabajo Julián!

And it got USFDA approval today. It is better strategy than post op nivo alone as probably neo adjuvant IO does the job . Will I like to read full paper published? Yes . U.S. FDA is really fast now a days 🙂

Hoy nos tocó coordinar la sesión académica en nuestro Instituto Instituto Nacional de Cancerología junto al jefe de residentes Kevin Reyna . Una sesión llena de mensajes valiosos.

🆕 FDA grants accelerated approval to Dato-DXd for EGFR-mutated NSCLC post-TKI + chemo 👏 But what’s the full picture? 🤔🧵 🔹 Based on 117 pts pooled from TROPION-Lung01 & Lung05 🔹 ORR: 43% | PFS: 5.8 mo | OS: 15.6 mo 📊 🔹 Prior osimertinib in 82% of pts 🔹 Common tox:

CUP is 2–5% of cancers but causes the 4th most cancer deaths. ⚠️ While tissue of origin can guide treatment, most patients see no clear benefit. ~33% have actionable mutations, targeted therapy won’t help all, but for some, it could change everything. rdcu.be/euSyo

Delighted and beyond excited! Amazing team Kevin Reyna Oscar Tahuahua along our professors and mentors #ESMO2025 here we go!