Another fantastic milestone for the #MRLinacconsortium - 500 peer reviewed publications and counting!

Glad that KWFKankerbestrijding will support the continued research collaboration between the departments of Radiation oncology at the The Netherlands Cancer Institute and Radboudumc to further personalize radiotherapy for patients with prostate cancer!
Uulke van der Heide, Floris Pos, Julia van Tol-Geerdink

Dr. David Palma presenting update on SABR-COMET. 25 months difference in OS and PFS, but no difference in time to 1st met! Tip of the iceberg in play: eat, sleep, SABR, REPEAT!

Thomas Zilli presenting STORM trial acute tox form nodal oligorecurrent PCa.
1. 80% restaged with PSMA PET
2. Higher PB RT use when ENRT was used.
3. ENRT does not increase acute G2 or higher GU or GI tox as comp to SBRT.
#ESTRO2022

Congratulations Matthias Guckenberger - delighted for you and for ESTRO 🎉👏

Great to have Anna Kirby as President and Ben Slotman as Past-President 🙏 #ESTRO2022

Great overview! Development and implementation of radiotherapy innovations definitely requires a different framework for clinical studies, as learned from surgical IDEAL framework @lennyverkooijen 𝖉𝖆𝖛𝖊 𝖋𝖚𝖑𝖑𝖊𝖗 @[email protected] frontiersin.org/articles/10.33…

Happy to continue the collaboration with top MR-linac centers and together bring MRI-guided RT to the next level! Proud of the Radboudumc team, Marcel Verheij, Ellen Brunenberg, Erik van der Bijl, Paulien Westhoff and many others! @lennyverkooijen William A Hall, MD John Christodouleas

We are very happy to welcome
Radboud UMC Radboudumc into the MOMENTUM family! Now that's 10 (and counting) major academic centers committed to working together to #learnfromeverypatient #MRLinac
@lennyverkooijen William A Hall, MD John Christodouleas Linda Kerkmeijer Elekta

Should we STAMPEDE to abiraterone for all patients with high-risk nonmetastatic prostate cancer? Reply to letter to the editor in European Urology authors.elsevier.com/c/1eo4Q14kplrI…

International Hybrid Conference

State-of-the-art, novel, and future PCa care; from diagnostics to therapeutics.

Focus on:
- local PCa
- low volume PCa
- local recurrent and metastatic mCRPC
- future.

International top-experts present their work:

radboudumc.nl/nijmegenprosta…

bit.ly/33kuBmA Interim results of the MIRAGE randomized trial of MRI-guided vs. CT-guided SBRT to be presented at #GU22 ASCO, suggesting significantly reduced acute GU≥2 and GI≥2 toxicity with MRI-guidance. .

Great paper by William A Hall, MD 𝖉𝖆𝖛𝖊 𝖋𝖚𝖑𝖑𝖊𝖗 @[email protected] and many other MR-linac colleagues on MRI-guided online adaptive radiotherapy. Next step in image-guided RT: definitely worth reading!

PSMA (or other novel imaging) to rule out distant Mets.

Then conversation with MulitD team about pros/cons of salvage #SBRT , #HDR and #RP

Amar Kishan MASTER meta-analysis shows equal efficacy but better tolerability for #HDR (more data needed for #SBRT but looks promising)

New Words of Wisdom from Jochen Walz

Re: Focal Boost to the Intraprostatic Tumor in External Beam Radiotherapy for Patients with Localized Prostate Cancer: Results from the FLAME Randomized Phase III Trial buff.ly/3rgGJOw

Great thread and article!

Stereotactic dose painting approach also used for prostate cancer in the hypo-FLAME study. Microscopic disease (whole prostate gland 35Gy in 5 fractions) and macroscopic disease (focal boost intraprostatic lesion up to 50Gy)

thegreenjournal.com/article/S0167-…

Online first: Androgen deprivation therapy use and duration with definitive #radiotherapy for localised #prostatecancer : an individual patient data meta-analysis thelancet.com/journals/lanon…

New article alert

Veerle H. Groen et al:
Urethral and bladder dose–effect relations for late genitourinary toxicity following external beam radiotherapy for prostate cancer in the FLAME trial. doi.org/10.1016/j.rado…

thegreenjournal.com/article/S0167-…

MRI-guided adaptive radiotherapy for urological cancers: what Urologists should know European Urology
Many thanks to Alison Tree 💙🇺🇦 Amar Kishan

authors.elsevier.com/a/1eOyu14kplnV…

#MRIgRT #prostatecancer #bladdercancer #kidneycancer European Association of Urology (EAU)

Great work from Martin Ma (he is on a roll) with a dosimetric post-hoc analysis of a subset of MRgRT patients on our MIRAGE RCT of MR-guided SBRT vs. CT-guided SBRT. sciencedirect.com/science/articl… (1/n)

🎄came a little early this year! RAPPORT trial out now, thank you @ELS_Oncology for providing 50-day link here; authors.elsevier.com/a/1eIB214kplnV…. This trial evaluated total metastatic irradiation in oligometastatic #kidneycancer + short course #immunotherapy . #radonc