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As a Californian on a pediatrics rotation in the Deep South, I asked a little girl a question about her pee. The girl started laughing and her mom looked shocked. Turns out “pee” is too crude to use with kids there. The correct term is “tee tee,” which was new to me.

Doctor who gave a lecture in med school: "If coffee and soda dehydrated you, a lot of my patients would be dead." (Because that's all they drink.)

I talk to doctors who want to get in on this AI opportunity window. They usually think they need to understand how AI works. So did I. Fascinating stuff, but our alpha is in using AI, not building it. Which is why my #1 recommendation is to focus on GREG ISENBERG’s content.

Anger’s sometimes what you need. For example, I want to work on business, but have a few life projects that need to get done soon. E.g. packing for a move. When I allow myself to be angry those things aren’t done, they get done. Ruthlessly.

Glad to find out kids would be better off without kid’s music

I hope whoever created this fake account steps in gum.

Never thought I’d miss the old ChatGPT voices. New ones are trying too hard to be cool.

I received an email from the founder of a growing company asking why I’d cancelled. I sent a thoughtful reply explaining my customer journey and even said I was reactivating. Someone other than the founder emailed back, essentially, “ok thx.” Don’t send fake founder emails.

Myostatin inhibitors are on the way. Make muscles stronger more easily. Unfortunately for muscle enthusiasts, they’re monoclonal antibodies, which are expensive to produce. So unlikely to have a thriving gray market like GLP-1s.

Part of getting older is fear that any incoming call from your parents is going to be bad news.

When Netflix streaming was first released, there was concern that internet service providers couldn’t handle that much traffic without significantly raising prices. I don’t know how, but it all worked out. I predict concerns about AI over-usage will turn out the same way.

Imagine explaining to a space alien what’s going on here. Ritualized combat with countless unspoken rules.

Apple's Foundation Models framework now lets iOS devs call Apple's on-device local model. Key takeaway is that it should be good at everything except advanced reasoning and general world knowledge. Let the building begin.

People with bipolar disorder startle more easily. Nicotine partially relieves this problem. This is thought to contribute to higher rates of smoking in these patients. I suspect there are many undiscovered incentives like this influencing our habits.