Congratulations 'We Found Grubbs in a Hyp(atulone)less Place GSK University of Strathclyde for winning the audience prize at the 2021 UK Retrosynthesis competition! #UKRetroComp

Winning the hearts of the audience today at #UKRetroComp Thank you to the organising committee and all those who voted for us. A huge well done to the team for putting a ring (CM) on it! Arron Aatkar Elliot Davenport Katharine Gilbert Karina Chan Connor Livingstone🏴󠁧󠁢󠁳󠁣󠁴󠁿🇺🇦🇪🇺

Our new paper is out in Nature Chemical Biology where we describe our journey from a #covalent fragment screen to an in vivo active Pin1 inhibitor. nature.com/articles/s4158… Below is a musical abstract guest-starring Uri Alon and a tweetorial 1/n

Hate is a strong word. But the racist relying on black English footballers to bring them glory as if they were their servants, then turning on them as soon as they fell short of their dreams, have my deepest contempt.

AlphaFold2 has done it again!

Congratulations to Karina Chan University of Strathclyde, Kate Gilbert GSK & Laia Josa-Cullere Institute for Advanced Chemistry of Catalonia, winners of the 2021 #EFMC_YMCS Poster Prizes sponsored by ChemMedChem, ChemBioChem & Chemistry Europe. EFMC EFMC Young Scientists Network #medchem #chembio #euromedchemtalents #medchemtalents

Covalent Inhibition of SARS-CoV-2 RBD-ACE2 Interaction by Aptamers with Multiple Sulfur(VI) Fluoride Exchange Modifications dlvr.it/S8rKWm

So excited to share our work profiling sulfonyl fluorides as powerful functionalities for chemical biology - chemrxiv.org/engage/chemrxi…

Beyond-cysteine #covalentmodifiers: check out Kate’s work on sulfonyl fluorides as powerful tools for #chemicalbiology in ChemRxiv. Great collab with GSK, Chemistry - University of Strathclyde and The Francis Crick Institute. Congrats to Katharine Gilbert and co-authors! #chembio chemrxiv.org/engage/chemrxi…

Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome dlvr.it/SJM0sV

This is a chemical biology must read !

Interesting ChemRxiv preprint by a team of GSK and Chemistry - University of Strathclyde around first author Katharine Gilbert and corresponding author Jacob Bush. The hydrolytic stability, amino acid reactivity and proteome-wide reactivity of various Sulfur(VI) Fluorides. doi.org/10.26434/chemr…

👀 First independent paper with over 100 citations. Might not be a big deal for some, but it important to share the impact of undergraduate research. I am proud of the work we do. Thanks to the amazing women of color for making this possible. Pomona College CUR Chemistry

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Let there be light: PhABits A library of unpurified photo-affinity fragments allows screens for binders anywhere on a protein practicalfragments.blogspot.com/2022/02/photoa… Jacob Bush GSK Chemical Science

Why spend 4 minutes doing something in Excel when you can do it in R in 4 hours?

rage against the machine never specified what machine they were raging against but i bet it was a mass spectrometer

Check out Arron Aatkar’s work taking reactive fragments into new landscapes: beyond-cysteine covalent ligand discovery with sulfonyl fluorides ChemRxiv. Great collab GSK, Chemistry - University of Strathclyde, The Francis Crick Institute. #chemicalbiology #covalentmodifiers (Artwork Emma Grant) lnkd.in/eec64JRZ

Very excited to share my work on reactive fragment screening with sulfonyl fluorides - check out the article on ChemRxiv! Many thanks to all co-authors for their contributions.

Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments [Arron Aatkar] dlvr.it/SfJZpN